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评《复发性流产患者生化妊娠流产的临床意义：来自整倍体胚胎移植的见解，最小化胚胎偏差》

Comment on "Clinical Significance of Biochemical Pregnancy Loss in Recurrent Pregnancy Loss Patients: Insights From Euploid Embryo Transfers Minimizing Embryonic Bias".

作者信息

Satapathy Prajnasini, Mehta Rachana, Sah Ranjana

机构信息

Center for Global Health Research Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University Chennai India.

S.R. Sanjeevani Hospital Kalyanpur Nepal.

出版信息

Reprod Med Biol. 2025 Sep 1;24(1):e12674. doi: 10.1002/rmb2.12674. eCollection 2025 Jan-Dec.

DOI:10.1002/rmb2.12674
PMID:40901053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12400155/
Abstract

This commentary addresses Kuwabara et al.'s study on biochemical pregnancy loss (BPL) in recurrent pregnancy loss (RPL) patients following euploid embryo transfers. While their methodology minimizes embryonic bias and strengthens maternal factor assessment, concerns regarding statistical interpretation and potential ascertainment bias limit generalizability. Nonetheless, this study raises important questions regarding the incorporation of BPL into RPL diagnostic frameworks.

摘要

本评论讨论了桑原等人关于整倍体胚胎移植后复发性流产（RPL）患者生化妊娠丢失（BPL）的研究。虽然他们的方法将胚胎偏差降至最低，并加强了母体因素评估，但对统计解释和潜在的确诊偏差的担忧限制了其普遍性。尽管如此，这项研究提出了关于将BPL纳入RPL诊断框架的重要问题。

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Comment on "Clinical Significance of Biochemical Pregnancy Loss in Recurrent Pregnancy Loss Patients: Insights From Euploid Embryo Transfers Minimizing Embryonic Bias".评《复发性流产患者生化妊娠流产的临床意义：来自整倍体胚胎移植的见解，最小化胚胎偏差》
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本文引用的文献

1
Clinical Significance of Biochemical Pregnancy Loss in Recurrent Pregnancy Loss Patients: Insights From Euploid Embryo Transfers Minimizing Embryonic Bias.复发性流产患者生化妊娠丢失的临床意义：来自整倍体胚胎移植的见解，最小化胚胎偏倚
Reprod Med Biol. 2025 Jul 23;24(1):e12668. doi: 10.1002/rmb2.12668. eCollection 2025 Jan-Dec.
2
Pitfalls of analyzing perinatal outcomes by health care provider.按医疗服务提供者分析围产期结局的陷阱。
CMAJ. 2023 Apr 24;195(16):E589. doi: 10.1503/cmaj.148294-l.