Han Chao, Guo Ning, Wang Jie, Xie Miao, Li Fei
Department of Thoracic and Cardiac Surgery, Puren Hospital affiliated to Wuhan University of Science and Technology School of Medicine, Wuhan, China.
Department of Gastrointestinal Surgery, Puren Hospital affiliated to Wuhan University of Science and Technology School of Medicine, Wuhan, China.
Ann Med Surg (Lond). 2025 Aug 1;87(9):6186-6192. doi: 10.1097/MS9.0000000000003653. eCollection 2025 Sep.
Cardiac atherosclerotic disease (CAD), the leading cause to cardiovascular disease-related death, coexisting with cardiac myxoma, the commonest benign primary cardiac neoplasm, is rare. The treatment of the comorbidity is complicated due to the rarity and inexperience.
A 65-year old male patient with intermittent chest tightness and shortness of breath for 10 years was admitted for further work-up. On admission, the comprehensive metabolic panel (CMP) revealed a normal liver, kidney and coagulant function, and the BNP, troponin and CK-MB were within the normal limits. ECG showed a sinus rhythm. Cardiac catheterization revealed a three-vessel disease of CAD. Incidentally, echocardiography and MRI found a mobile mass, highly suspicious of cardiac myxomas on the imaging, at the left atrium. A coronary artery bypass grafting (CABG) combining with a right-atrium approach resection of the lesion were devised and concomitantly performed. No surgical complications and major cardiac adverse events occurred post-procedure. After anti-infection and supportive care, the patient recovered uneventfully. Follow-up at 6 months revealed no discomfort of the patient.
It was risky to treat the comorbidity separately. Due to the rarity of the comorbidity, it remains unsolved whether the prognosis will be truly affected by the concurrent procedures. Yet, this single case with a prosperous outcome post-surgery might provide a valuable reference to the treatment of cardiac myxomas incidentally diagnosed in CAD.
The three-vessel CAD co-occurring with the single lesion cardiac myxomas at the left atrium can be managed safely and effectively by combining CABG with transseptal right atriotomy in the concomitant procedures.
心脏动脉粥样硬化疾病(CAD)是心血管疾病相关死亡的主要原因,与最常见的原发性心脏良性肿瘤心脏黏液瘤并存的情况较为罕见。由于这种合并症的罕见性以及经验不足,其治疗较为复杂。
一名65岁男性患者,间歇性胸闷、气短10年,入院进一步检查。入院时,综合代谢指标(CMP)显示肝、肾及凝血功能正常,脑钠肽(BNP)、肌钙蛋白及肌酸激酶同工酶(CK-MB)均在正常范围内。心电图显示窦性心律。心脏导管检查发现CAD三支血管病变。偶然发现,超声心动图和磁共振成像(MRI)在左心房发现一个活动肿物,影像学上高度怀疑为心脏黏液瘤。设计并同时进行了冠状动脉旁路移植术(CABG)联合经右心房入路切除病变。术后未发生手术并发症及严重心脏不良事件。经过抗感染及支持治疗,患者顺利康复。6个月随访显示患者无不适。
分别治疗这种合并症存在风险。由于这种合并症罕见,同时进行的手术是否真的会影响预后尚无定论。然而,这例术后效果良好的单一病例可能为CAD中偶然诊断出的心脏黏液瘤的治疗提供有价值的参考。
左心房单发病变的心脏黏液瘤合并三支血管CAD,可通过在同期手术中联合CABG与经房间隔右心房切开术安全有效地进行治疗。