Rowe G P, Bowell P
Vox Sang. 1985;49(6):400-2. doi: 10.1111/j.1423-0410.1985.tb01132.x.
A positive direct antiglobulin reaction of a baby's cells, found during antenatal testing at Cardiff, was caused by a low-frequency antigen which has been identified as Rea (ISBT No. 700019). Investigations with this, only the second example, anti-Rea revealed another Re(a+) propositus in testing 6,635 random donors at Oxford; no further positive was found in 4,770 random donors at Cardiff. Study of the families of these two propositi, the first to be identified since the original Canadian family, confirmed that Rea was inherited as an autosomal Mendelian dominant. The families showed that Rea is not controlled by the ABO, Kell or Au loci and confirmed that it was not controlled by MNSs and was not X- or Y-borne.
在加的夫进行产前检测时，发现一名婴儿细胞的直接抗球蛋白反应呈阳性，这是由一种低频抗原引起的，该抗原已被鉴定为Rea（国际输血协会编号700019）。对这一仅为第二例的样本进行研究时，抗Rea在牛津对6635名随机供血者的检测中又发现了一名Re(a+)先证者；在加的夫对4770名随机供血者的检测中未发现其他阳性结果。对这两名先证者（自最初的加拿大家庭以来首次被鉴定）的家族进行研究后证实，Rea是作为常染色体孟德尔显性遗传的。这些家族表明，Rea不受ABO、凯尔或Au基因座控制，并证实它不受MNSs控制，也不是X或Y连锁的。
