Atanasova P, Milkov V
Vutr Boles. 1985;24(5):97-9.
Two cases are described with paraneoplastic amyloidosis, advancing in patients with a basic etiological moment--myeloma and hypernephroma. The clinical picture, in both patients was dominated by the nephrotic syndrome and rapidly progressing renal insufficiency, leading to the fatal end within a very short term. That term in the patient with hypernephroma was only several months after making the diagnosis, and in the patient with myeloma--up to two years. Renal punch biopsy was performed to both patients during their life time.
本文描述了两例副肿瘤性淀粉样变性病例,患者分别患有原发性病因——骨髓瘤和肾细胞癌。两名患者的临床表现均以肾病综合征和快速进展的肾功能不全为主,在短期内导致致命结局。肾细胞癌患者在确诊后仅数月,骨髓瘤患者则长达两年。两名患者在生前均接受了肾穿刺活检。