Dadpe Mahesh Vilasrao, Shelke Pooja Balaji, Kale Yogesh Jagannath, Dahake Prasanna Trambakrao, Kendre Shrikant Bhujangrao, Mankar Shrawani
Department of Pediatric and Preventive Dentistry, MIDSR Dental College, Latur, Maharashtra, India.
Dent Res J (Isfahan). 2025 Aug 25;22:33. doi: 10.4103/drj.drj_205_23. eCollection 2025.
The goal of this study was to assess the techniques used in earlier conducted clinical investigations on the chemomechanical eradication of dentinal caries, as well as to assess the variances in pain perception, the time required for complete caries excavation, and how microbiological analysis compared before and following caries removal in primary teeth for both Papacarie and Carisolv.
An electronic search was conducted utilizing the databases PubMed, Google Scholar, EBSCOhost, Scopus, and the Cochrane Library. The following categories were included during the assessment process: full text randomized and controlled clinical trials published between January 2000 and December 2021 in the English language only. Adolescent and child patients with open dentinal carious lesion in primary teeth were included. The methodology of the seven clinical studies chosen was evaluated.
Findings of the study reported that the microbiota in carious dentine was dramatically reduced with the Papacarie therapy, and the pain perception decreased more in the Papacarie group, whereas Carisolv treatment took longer time for complete caries excavation as compared to Papacarie.
In conclusion, Papacarie had a beneficial impact by decreasing pain and time taken during caries excavation in primary teeth. The tooth surface treated with Papacarie also demonstrated a reduced bacterial count as compared to Carisolv chemomechanical caries removal approach. Overall, Papacarie and Carisolv are viable minimally invasive and painless techniques for effective caries removal in pediatric patients.
本研究的目的是评估早期进行的关于化学机械性根除牙本质龋的临床研究中所使用的技术,以及评估在乳牙中使用帕帕卡里(Papacarie)和卡利索尔夫(Carisolv)进行龋病去除前后,疼痛感知的差异、完全去除龋坏组织所需的时间,以及微生物分析的对比情况。
利用PubMed、谷歌学术、EBSCOhost、Scopus和考克兰图书馆数据库进行电子检索。评估过程中纳入以下类别:2000年1月至2021年12月期间仅以英文发表的全文随机对照临床试验。纳入患有乳牙开放性牙本质龋损的青少年和儿童患者。对所选的七项临床研究的方法进行了评估。
研究结果报告称,帕帕卡里治疗可使龋坏牙本质中的微生物群显著减少,且帕帕卡里组的疼痛感知下降更多,而与帕帕卡里相比,卡利索尔夫治疗完成龋坏组织去除所需的时间更长。
总之,帕帕卡里通过减少乳牙龋病去除过程中的疼痛和时间产生了有益影响。与卡利索尔夫化学机械性龋病去除方法相比,用帕帕卡里治疗的牙面细菌计数也有所减少。总体而言,帕帕卡里和卡利索尔夫是用于儿科患者有效去除龋病的可行的微创无痛技术。