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梅克尔憩室:儿童与成人临床特征的差异

Meckel's diverticulum: differences in clinical features between children and adults.

作者信息

Srisan N, Songsiri P, Liukitithara S, Sriniworn A, Decharun K, Rajatapiti P, Reukvibunsi S, Nonthasoot B, Prichayudh S, Tharavej C, Manasnayakorn S, Vejchapipat P

机构信息

Department of Surgery, Faculty of Medicine, Chulalongkorn University & King Chulalongkorn Memorial Hospital, Bangkok, 10330, Thailand.

Department of Surgery, Hat Yai Hospital, Songkhla, 90110, Thailand.

出版信息

Pediatr Surg Int. 2025 Sep 4;41(1):284. doi: 10.1007/s00383-025-06183-8.

Abstract

PURPOSE

The objectives were to describe and to compare the clinical features of patients with MD in terms of demographic data, clinical presentation, investigations, treatment, histopathology, and postoperative complications between children and adults.

METHODS

Patients with MD were retrospectively reviewed from two tertiary hospitals (2002-2021). These included patients with symptomatic MD and patients whose MD was incidentally found during operations. Demographic data, clinical presentation, investigation, treatment, histopathology, and postoperative complications were reviewed.

RESULTS

A total of 123 cases with MD (69 children vs 54 adults) were studied. Of 69 children with MD, symptomatic MD was reported in 48 cases (69.6%). Lower GI bleeding was the most common presentation (52.1%), followed by obstruction (29.1%), umbilical problems (10.4%), and diverticulitis (8.3%). For children with bleeding MD (25 cases), Meckel scan was an important investigation to confirm the diagnosis, with a sensitivity value of 95%. Of 54 adults with MD, symptomatic MD was recorded in 30 cases (55.6%). Diverticulitis was the most common presentation (46.7%), followed by obstruction (30.0%), GI bleeding (20.0%), and umbilical problems (3.3%). For incidentally found MD during operations, 80% were resected. Interestingly, ectopic gastric tissue was found in 27.4% of the resected MD specimens. Moreover, there was no significant difference in postoperative complications between patients with symptomatic MD and patients with incidentally found MD.

CONCLUSION

The most common symptom of MD was lower GI bleeding in children, and diverticulitis in adults. Meckel scan is an important tool to investigate bleeding MD. Since ectopic gastric tissue was found in 19% of asymptomatic MD, our findings seem to support the concept of resection of MD incidentally found during the operations.

摘要

目的

本研究旨在从人口统计学数据、临床表现、检查、治疗、组织病理学以及儿童和成人术后并发症等方面描述并比较患有梅克尔憩室(MD)患者的临床特征。

方法

对两家三级医院(2002年至2021年)的MD患者进行回顾性研究。这些患者包括有症状的MD患者以及手术中偶然发现MD的患者。回顾了人口统计学数据、临床表现、检查、治疗、组织病理学和术后并发症。

结果

共研究了123例MD患者(69例儿童,54例成人)。在69例儿童MD患者中,48例(69.6%)报告有症状。下消化道出血是最常见的表现(52.1%),其次是梗阻(29.1%)、脐部问题(10.4%)和憩室炎(8.3%)。对于有出血症状的儿童MD患者(25例),梅克尔扫描是确诊的重要检查方法,敏感度为95%。在54例成人MD患者中,30例(55.6%)有症状。憩室炎是最常见的表现(46.7%),其次是梗阻(30.0%)、消化道出血(20.0%)和脐部问题(..3%)。对于手术中偶然发现的MD,80%进行了切除。有趣的是,在切除的MD标本中,27.4%发现了异位胃组织。此外,有症状的MD患者和偶然发现的MD患者术后并发症无显著差异。

结论

MD在儿童中最常见的症状是下消化道出血,在成人中是憩室炎。梅克尔扫描是检查出血性MD的重要工具。由于在19%无症状的MD中发现了异位胃组织,我们的研究结果似乎支持手术中偶然发现的MD进行切除的观点。 (注:原文中“3.3%”前面的“..”为原文错误,翻译时保留)

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