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Regulatory Interplay of p53, AMPK, and mTOR in Decidualization: Implications for Reproductive Competence and Cancer Biology.

作者信息

Kobayashi Hiroshi, Shigetomi Hiroshi, Nishio Miki, Umetani Mai, Imanaka Shogo, Hashimoto Hiratsugu

机构信息

Department of Gynecology and Reproductive Medicine, Ms.Clinic MayOne, 871-1 Shijo-cho, Kashihara, 634-0813, Japan.

Department of Obstetrics and Gynecology, Nara Medical University, 840 Shijo-cho, Kashihara, 634-8522, Japan.

出版信息

Reprod Sci. 2025 Sep 4. doi: 10.1007/s43032-025-01970-z.

DOI:10.1007/s43032-025-01970-z
PMID:40908401
Abstract
摘要

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本文引用的文献

1
Molecular Mechanisms of Cellular Senescence in Age-Related Endometrial Dysfunction.衰老相关子宫内膜功能障碍中细胞衰老的分子机制
Cells. 2025 Jun 6;14(12):858. doi: 10.3390/cells14120858.
2
Endometrial Aging and Reproductive Decline: The Central Role of Mitochondrial Dysfunction.子宫内膜衰老与生殖功能衰退:线粒体功能障碍的核心作用
Int J Mol Sci. 2025 May 24;26(11):5060. doi: 10.3390/ijms26115060.
3
ATM and p53 in aging and cancer: a double-edged sword in genomic integrity.衰老与癌症中的ATM和p53:基因组完整性中的双刃剑
Biogerontology. 2025 May 5;26(3):102. doi: 10.1007/s10522-025-10249-4.
4
Glucose metabolism and endometrium decidualization.葡萄糖代谢与子宫内膜蜕膜化
Front Endocrinol (Lausanne). 2025 Feb 17;16:1546335. doi: 10.3389/fendo.2025.1546335. eCollection 2025.
5
Lactate Promotes Hypoxic Granulosa Cells' Autophagy by Activating the HIF-1α/BNIP3/Beclin-1 Signaling Axis.乳酸通过激活HIF-1α/BNIP3/Beclin-1信号轴促进缺氧颗粒细胞的自噬。
Genes (Basel). 2024 Dec 26;16(1):14. doi: 10.3390/genes16010014.
6
Effects of hypoxia on uteroplacental and fetoplacental vascular function during pregnancy.孕期缺氧对子宫胎盘和胎儿胎盘血管功能的影响。
Front Physiol. 2024 Dec 18;15:1490154. doi: 10.3389/fphys.2024.1490154. eCollection 2024.
7
Age-related uterine changes and its association with poor reproductive outcomes: a systematic review and meta-analysis.年龄相关性子宫变化及其与不良生殖结局的关系:系统评价和荟萃分析。
Reprod Biol Endocrinol. 2024 Nov 30;22(1):152. doi: 10.1186/s12958-024-01323-6.
8
Progesterone increases metabolism via the pentose phosphate pathway in bovine uterine epithelial cells.孕酮通过戊糖磷酸途径增加牛子宫内膜上皮细胞的代谢。
Mol Biol Rep. 2024 Oct 19;51(1):1076. doi: 10.1007/s11033-024-10001-0.
9
Linking DNA damage and senescence to gestation period and lifespan in placental mammals.将胎盘哺乳动物的DNA损伤和衰老与妊娠期及寿命联系起来。
Front Cell Dev Biol. 2024 Sep 30;12:1480695. doi: 10.3389/fcell.2024.1480695. eCollection 2024.
10
transfer of decidualized endometrial stromal cells increases the frequency of regulatory T cells and normalizes the abortion rate in the CBA/J × DBA/2 abortion model.蜕膜化子宫内膜基质细胞的转移增加了调节性 T 细胞的频率,并使 CBA/J×DBA/2 流产模型中的流产率正常化。
Front Immunol. 2024 Sep 23;15:1440388. doi: 10.3389/fimmu.2024.1440388. eCollection 2024.