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经导管主动脉瓣置换术后伪装成肺栓塞的主动脉夹层伴假性动脉瘤形成

Aortic Dissection With Pseudoaneurysm Formation Masquerading as Pulmonary Embolism After Transcatheter Aortic Valve Replacement.

作者信息

Wang Heather, Bello Juan, Gala Dhir, Lander Jeffrey S

机构信息

Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.

Cooperman Barnabas Medical Center, Livingston, New Jersey, USA.

出版信息

Catheter Cardiovasc Interv. 2025 Nov;106(5):2969-2974. doi: 10.1002/ccd.70148. Epub 2025 Sep 5.

DOI:10.1002/ccd.70148
PMID:40908904
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12584563/
Abstract

Transcatheter aortic valve replacement (TAVR) is a commonly performed procedure for the treatment of severe aortic stenosis. While it is generally considered a low-risk procedure, one of the rare potentially life-threatening complications includes aortic dissection. We report the case of a 75-year-old immunocompromised female who presented 2 weeks post-TAVR with persistent and worsening dyspnea, intermittent chest pain, and hypoxia. The patient's symptoms and risk factors increased the suspicion for pulmonary embolism, and initial imaging was supportive of the diagnosis. Management with therapeutic anticoagulation did not resolve the symptoms, and the patient developed acute-onset anemia. Further investigation revealed an aneurysmal dilation and dissection of the ascending thoracic aorta with pseudoaneurysm causing near-complete obstruction of the right pulmonary artery. This case highlights the diagnostic challenges of a rare and delayed post-TAVR complication and describes a unique presentation of aortic dissection. Post-operative complications should be considered in diagnosis even weeks after the procedure.

摘要

经导管主动脉瓣置换术(TAVR)是治疗严重主动脉瓣狭窄的常用手术。虽然它通常被认为是一种低风险手术,但罕见的潜在危及生命的并发症之一包括主动脉夹层。我们报告了一例75岁免疫功能低下女性的病例,该患者在TAVR术后2周出现持续且加重的呼吸困难、间歇性胸痛和低氧血症。患者的症状和危险因素增加了对肺栓塞的怀疑,初步影像学检查支持该诊断。抗凝治疗未能缓解症状,患者出现急性贫血。进一步检查发现升主动脉瘤样扩张并伴有夹层形成,假性动脉瘤导致右肺动脉几乎完全阻塞。本病例突出了TAVR术后罕见且延迟并发症的诊断挑战,并描述了主动脉夹层的独特表现。即使在手术后数周,诊断时也应考虑术后并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61c9/12584563/01d685352894/CCD-106-2969-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61c9/12584563/346b3a2cf396/CCD-106-2969-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61c9/12584563/01d685352894/CCD-106-2969-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61c9/12584563/346b3a2cf396/CCD-106-2969-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61c9/12584563/01d685352894/CCD-106-2969-g002.jpg

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本文引用的文献

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JACC Case Rep. 2024 Nov 6;29(21):102692. doi: 10.1016/j.jaccas.2024.102692.
2
Acute Aortic Dissection After Transcatheter Aortic Valve Replacement.经导管主动脉瓣置换术后急性主动脉夹层。
Am J Cardiol. 2024 Jul 1;222:108-112. doi: 10.1016/j.amjcard.2024.04.059. Epub 2024 May 14.
3
Pseudoaneurysm after TAVR: how to close the hole?经导管主动脉瓣置换术(TAVR)后假性动脉瘤:如何封堵破口?
Eur Heart J Cardiovasc Imaging. 2023 May 31;24(6):e102. doi: 10.1093/ehjci/jead047.
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Ascending Aorta Pseudoaneurysm as a Rare, Late Complication after Valve-in-Valve Transcatheter Aortic Valve Implantation Procedure.升主动脉假性动脉瘤作为经导管主动脉瓣置入术(瓣中瓣技术)罕见的晚期并发症。
Acta Cardiol Sin. 2022 Sep;38(5):642-645. doi: 10.6515/ACS.202209_38(5).20220330C.
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Ascending Aortic Pseudoaneurysm: A Rare Complication of Transcatheter Aortic Valve Replacement and Thoracic Surgery.升主动脉假性动脉瘤:经导管主动脉瓣置换术和胸外科手术的罕见并发症
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