Shamoto Noritoshi, Naito Yushi, Sano Yuta, Matsuo Kazuna, Inoue Satoshi, Sano Tomoyasu, Kimura Tomokazu, Ishida Shohei, Matsukawa Yoshihisa, Akamatsu Shusuke
Department of Urology Nagoya University Graduate School of Medicine Nagoya Japan.
IJU Case Rep. 2025 Jul 10;8(5):485-488. doi: 10.1002/iju5.70073. eCollection 2025 Sep.
Tumor development in the ileal conduit is rare. Herein, we present a case of metastatic malignant melanoma occurring within the ileal conduit 17 years after radical cystectomy.
A 76-year-old Japanese man, with a history of bladder cancer treated with radical cystectomy and ileal conduit diversion, presented with gross hematuria. He had malignant melanoma diagnosed 10 years prior, with recurrent metastases managed through surgery and adjuvant therapy. During his recent admission, metastases to the subcutaneous tissue and retroperitoneum were noted. Contrast-enhanced computed tomography revealed bilateral hydronephrosis and a tumor in the ileal conduit. Endoscopic resection confirmed metastatic malignant melanoma. The patient's renal function stabilized postoperatively, and hematuria was controlled. A palliative care approach was adopted to treat the melanoma.
This rare case of metastatic malignant melanoma within an ileal conduit highlights the importance of histopathological examinations in patients with overlapping malignancies. 2016-0474.
回肠代膀胱内发生肿瘤极为罕见。在此，我们报告一例在根治性膀胱切除术后17年，回肠代膀胱内出现转移性恶性黑色素瘤的病例。
一名76岁的日本男性，有膀胱癌病史，接受过根治性膀胱切除术及回肠代膀胱术，现出现肉眼血尿。他10年前被诊断为恶性黑色素瘤，复发性转移通过手术和辅助治疗进行处理。在他最近一次入院期间，发现皮下组织和腹膜后有转移。增强计算机断层扫描显示双侧肾积水以及回肠代膀胱内有一个肿瘤。内镜切除证实为转移性恶性黑色素瘤。患者术后肾功能稳定，血尿得到控制。采用姑息治疗方法来治疗黑色素瘤。
这例罕见的回肠代膀胱内转移性恶性黑色素瘤病例凸显了对合并恶性肿瘤患者进行组织病理学检查的重要性。2016 - 0474。
