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罗勒(唇形科罗勒属):一种天然的皮肤护理方法及其药妆潜力。

Basil (Ocimum basilicum): A Natural Approach to Skin Care and Its Cosmeceutical Potential.

作者信息

Gupta Divyanshi, Chaurasia Harshit, Verma Shivam, Gupta Shreya, Chauhan Vaishnavi, Wal Ankita

机构信息

PSIT-Pranveer Singh Institute of Technology (Pharmacy), Bhauti-Kanpur, Uttar Pradesh, 209305, India.

出版信息

Curr Drug Discov Technol. 2025 Aug 27. doi: 10.2174/0115701638372091250812093301.

DOI:10.2174/0115701638372091250812093301
PMID:40910211
Abstract

INTRODUCTION

Basil, an indigenous medicinal herb, is widely used in traditional medicine for its therapeutic and cosmetic benefits. Its properties include reducing oxidative stress, increasing melatonin production, protecting cells from free radical damage, and protecting the skin. Basil can be incorporated into daily skincare routines to address various skin conditions and promote overall health. This study examines the role of Basil in skin health, focusing on its antioxidant, antiinflammatory, antimicrobial, hydrating, and moisturizing properties. It examines its bioactive compounds and their impact on molecular pathways, such as NF-κB, MAPK, and COX-LOX, in reducing oxidative stress and inflammation. Additionally, it highlights Basil's potential as an anti-aging agent and its applications in skincare products.

METHOD

The data were gathered from various research studies and meta-analyses on basil cosmetics applications, sourced from multiple databases between 1999 and 2025, including PubMed, ScienceDirect, SpringerLink, Wiley Online Library, Elsevier, Nature, ResearchGate, and Google Scholar.

RESULT

Basil enhances skin health through its antioxidant, anti-inflammatory, antimicrobial, hydrating, and moisturizing effects. Its bioactive compounds, including flavonoids, phenolic acids, and terpenes, help neutralize ROS and RNS, preventing oxidative damage and inflammation. By modulating key inflammatory pathways, such as NF-κB, MAPK, and COX-LOX, Basil reduces proinflammatory cytokines and inhibits inflammatory mediators. These mechanisms contribute to its anti-aging and skin-protective properties, making it beneficial for various skincare applications.

DISCUSSION

Basil is an indigenous herb with significant therapeutic potential. Traditionally, it has been used to manage various skin conditions, including acne and eczema. Studies have highlighted its anti-inflammatory and antioxidant properties, primarily due to its ability to inhibit the generation of free radicals. Additionally, Basil exhibits potent antimicrobial activity, attributed to the presence of essential oils that disrupt microbial cell membranes, inhibit biofilm formation, increase membrane permeability, and lead to intracellular leakage. Owing to these multifaceted properties, Basil holds promise for use in dermatological applications and cosmetic formulations.

CONCLUSION

Basil, a popular herb in various cultures, has antioxidant properties and is used in traditional medicine, skincare, and beauty treatments. Its essential oils, including linalool, estragole, and eugenol, have anti-aging, antifungal, and antibacterial properties. Basil's complex phytochemical composition makes it an excellent component for skincare, hair care, and dental care products. Its bioactive compounds neutralize reactive oxygen species and reactive nitrogen species, preventing oxidative damage and inflammation. Further research and clinical validation could enhance Basil's application in dermatology and cosmetic industries.

摘要

引言

罗勒是一种本土药草,因其治疗和美容功效在传统医学中被广泛使用。其特性包括减轻氧化应激、增加褪黑素生成、保护细胞免受自由基损伤以及保护皮肤。罗勒可纳入日常护肤程序中,以应对各种皮肤状况并促进整体健康。本研究探讨罗勒在皮肤健康中的作用,重点关注其抗氧化、抗炎、抗菌、保湿和滋润特性。研究其生物活性化合物及其对分子途径(如核因子κB、丝裂原活化蛋白激酶和环氧化酶-脂氧合酶)的影响,以减轻氧化应激和炎症。此外,还强调了罗勒作为抗衰老剂的潜力及其在护肤品中的应用。

方法

数据收集自1999年至2025年间多个数据库中关于罗勒在化妆品应用方面的各种研究和荟萃分析,这些数据库包括PubMed、ScienceDirect、SpringerLink、Wiley Online Library、Elsevier、Nature、ResearchGate和谷歌学术。

结果

罗勒通过其抗氧化、抗炎、抗菌、保湿和滋润作用增强皮肤健康。其生物活性化合物,包括黄酮类、酚酸类和萜类,有助于中和活性氧和活性氮,防止氧化损伤和炎症。通过调节关键的炎症途径,如核因子κB、丝裂原活化蛋白激酶和环氧化酶-脂氧合酶,罗勒减少促炎细胞因子并抑制炎症介质。这些机制有助于其抗衰老和皮肤保护特性,使其对各种护肤应用有益。

讨论

罗勒是一种具有显著治疗潜力的本土药草。传统上,它被用于治疗各种皮肤疾病,包括痤疮和湿疹。研究突出了其抗炎和抗氧化特性,主要归因于其抑制自由基生成的能力。此外,罗勒表现出强大的抗菌活性,这归因于其所含的精油,这些精油会破坏微生物细胞膜、抑制生物膜形成、增加膜通透性并导致细胞内物质泄漏。由于这些多方面的特性,罗勒在皮肤科应用和化妆品配方中具有应用前景。

结论

罗勒是各种文化中常见的药草,具有抗氧化特性,被用于传统医学、皮肤护理和美容治疗。其精油,包括芳樟醇、草蒿脑和丁香酚,具有抗衰老、抗真菌和抗菌特性。罗勒复杂的植物化学成分使其成为护肤品、护发品和口腔护理产品的优良成分。其生物活性化合物中和活性氧和活性氮,防止氧化损伤和炎症。进一步的研究和临床验证可能会增强罗勒在皮肤科和化妆品行业的应用。

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