Nagata Y, Kinoshita H, Kawamura N, Sasadaira S
Hinyokika Kiyo. 1985 Nov;31(11):1931-7.
We report on the immunohistochemical detection of carcinoembryonic antigen in the urine cytology of 5 patients with urinary bladder tumors classified as low, moderate, and high grade. Immunohistochemically carcinoembryonic antigens were detected in urine cytology in the case of moderate and high grade tumors, but not, low grade tumors. Carcinoembryonic antigen positivity in urine cytology correlated with the histological grade of a bladder tumor. Carcinoembryonic antigen in urine cytology seemed to be a potentially good marker to distinguish between high grade and low grade tumors.
我们报告了5例膀胱肿瘤患者尿液细胞学中癌胚抗原的免疫组化检测结果,这些肿瘤分为低级别、中级别和高级别。免疫组化检测发现,中级别和高级别肿瘤患者的尿液细胞学中可检测到癌胚抗原,而低级别肿瘤患者则未检测到。尿液细胞学中癌胚抗原阳性与膀胱肿瘤的组织学分级相关。尿液细胞学中的癌胚抗原似乎是区分高级别和低级别肿瘤的潜在良好标志物。