Benign Metastasizing Leiomyoma Presenting as a Right Ventricular Mass.
作者信息
Romano Edoardo, Schütze Jonathan, Schönhoff Florian, Siegenthaler Franziska, Banz Yara, Gräni Christoph
机构信息
Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Department of Cardiac Surgery, Inselspital Bern, University Hospital Bern, Bern, Switzerland.
出版信息
JACC Case Rep. 2025 Sep 3;30(26):104914. doi: 10.1016/j.jaccas.2025.104914.
BACKGROUND
Masses in the right ventricle are uncommon, but if present, they are most often attributed to either primary cardiac tumors or metastatic disease.
CASE SUMMARY
A 50-year-old woman presented with progressive lower extremity edema and was diagnosed with a right ventricular mass causing severe tricuspid insufficiency and near-total obstruction of the pulmonary artery. She had a history of hysterectomy for uterine leiomyomatosis. Based on imaging and histological findings, a diagnosis of benign metastasizing leiomyoma (BML) was made. The patient underwent successful resection of the mass, tricuspid valve replacement, and implantation of a right ventricle-pulmonary artery conduit.
DISCUSSION
Cardiac metastasis from BML is extremely rare, particularly in the right heart. Although histologically benign, BML can lead to life-threatening cardiac complications. This case emphasizes the importance of thorough cardiac assessment in patients with a history of leiomyoma and unexplained symptoms. Early diagnosis and surgical management are essential to prevent serious outcomes.
TAKE-HOME MESSAGES: BML, though rare, can cause life-threatening cardiac involvement. Clinicians should consider a comprehensive cardiac evaluation for patients with unexplained cardiac symptoms and a history of leiomyoma.
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