Advances that position intracellular calcium dysregulation as an emerging therapeutic target in heart disease.
作者信息
Alvarado Francisco J, Ríos Pérez Erick B
机构信息
Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin; Cardiovascular Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.
Division of Cardiovascular Medicine, Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin; Cardiovascular Research Center, University of Wisconsin-Madison School of Medicine and Public Health, Madison, Wisconsin.
出版信息
Heart Rhythm. 2025 Sep;22(9):2440-2441. doi: 10.1016/j.hrthm.2025.05.019.
Abstract
摘要
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RyR2 inhibition with dantrolene is antiarrhythmic, prevents further pathological remodeling, and improves cardiac function in chronic ischemic heart disease.丹曲林钠抑制 RyR2 具有抗心律失常作用，可防止慢性缺血性心脏病进一步的病理性重构，并改善心功能。
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