Futyma Piotr, Zarębski Łukasz, Garg Lohit, Mohanty Sanghamitra, La Fazia Vincenzo Mirco, Torlapati Prem Geeta, Marchlinski Francis E, Natale Andrea, Santangeli Pasquale
University of Rzeszów and St. Joseph's Heart Rhythm Center, Anny Jagiellonki 17, 35-623, Rzeszów, Poland.
Division of Cardiovascular Medicine, Electrophysiology Section, University of Colorado, Denver, CO, USA.
J Interv Card Electrophysiol. 2025 Sep 6. doi: 10.1007/s10840-025-02120-w.
Catheter ablation of scar-related interatrial septal atrial tachycardias (IAS-ATs) is challenging and can be refractory to conventional unipolar radiofrequency catheter ablation (RFCA).
This multicenter study investigated the safety and efficacy of bipolar radiofrequency catheter ablation (Bi-RFCA) in patients with IAS-AT refractory to conventional unipolar RFCA.
Consecutive patients with scar-related IAS-AT refractory to conventional unipolar RFA across three electrophysiological centers were included in the study. Bi-RFCA with power up to 40 W and duration up to 60 s was performed with two ablation catheters across the IAS at sites identified with activation and entrainment mapping. Acute termination and noninducibility of the targeted IAS-AT was used as the intraprocedural ablation endpoint. Arrhythmia-free survival from any atrial arrhythmia (AT or atrial fibrillation) lasting > 30 s was used as a follow-up outcome measure.
A total of 17 patients (12 males, age 62 ± 13) were included in the study. Acute elimination of arrhythmia with Bi-RFCA was achieved in all patients. Mean procedure time was 173 ± 69 min, mean bipolar RF time 209 ± 193 s, and mean power 39 ± 3 W. During 11 ± 3 months of follow-up, AT/AF recurrence was observed in 2 (12%) patients. No steam pops occurred during any of the Bi-RFCA applications and no other complications occurred during procedures or follow-up.
Bi-RFCA is an effective and safe strategy to target scar-related IAS-AT refractory to standard unipolar RFCA.
导管消融瘢痕相关的房间隔房性心动过速(IAS-ATs)具有挑战性,并且可能对传统的单极射频导管消融(RFCA)无效。
本多中心研究调查了双极射频导管消融(Bi-RFCA)对传统单极RFCA无效的IAS-AT患者的安全性和有效性。
本研究纳入了三个电生理中心连续的对传统单极RFA无效的瘢痕相关IAS-AT患者。使用两根消融导管在通过激动标测和拖带标测确定的部位横跨IAS进行功率高达40W、持续时间长达60秒的Bi-RFCA。以目标IAS-AT的急性终止和不能诱发作为术中消融终点。随访结果指标为持续时间超过30秒的任何房性心律失常(AT或房颤)的无心律失常生存期。
本研究共纳入17例患者(12例男性,年龄62±13岁)。所有患者均通过Bi-RFCA实现了心律失常的急性消除。平均手术时间为173±69分钟,平均双极射频时间为209±193秒,平均功率为39±3W。在11±3个月的随访期间,2例(12%)患者出现AT/AF复发。在任何Bi-RFCA应用过程中均未发生蒸汽泡,手术过程或随访期间未发生其他并发症。
Bi-RFCA是针对标准单极RFCA无效的瘢痕相关IAS-AT的一种有效且安全的策略。