用吲哚菁绿染料浸泡的栓塞线圈经皮标记肺肿瘤：肺保留手术中准确术中定位的视觉信标。

Lung Tumors Marked Percutaneously with Indocyanine Green Dye-Soaked Embolization Coils: A Visual Beacon for Accurate Intraoperative Localization during Lung-Sparing Surgery.

作者信息

Walsh Edward J, Bawaadam Hasnain, Mammarappallil Joseph G, Snider Jason R, Allsopp William C, Brodeur Frederick J, Green Aaron R, Krishna Ganesh, Wojcik Brandon M

机构信息

Grand Traverse Radiologists, Department of Radiology, Munson Medical Center, Traverse City, Michigan.

Department of Interventional Pulmonary and Critical Care Medicine, Advocate Aurora Medical Center Kenosha, Kenosha, Wisconsin.

出版信息

J Vasc Interv Radiol. 2025 Sep 4:107825. doi: 10.1016/j.jvir.2025.08.042.

DOI:10.1016/j.jvir.2025.08.042

PMID:40914488

Abstract

Thoracic surgeons using minimally invasive techniques for lung nodule resection often rely on localization markers to determine precise nodule location intraoperatively. Transbronchial or transthoracic injection of indocyanine green (ICG) dye has become a popular technique. However, surgery must be performed immediately before dye dissipates into surrounding tissue. This multicenter retrospective study evaluated the effectiveness of computed tomography (CT)-guided transthoracic placement of ICG dye-soaked coils (ICG-Cs) for preoperative lung nodule localization. Nineteen adult patients with 21 nodules underwent CT ICG-C placement from March 01, 2023, until February 28, 2025, at 2 medical centers. There were no adverse events. Median time from localization to surgery was 1 day (interquartile range, 0-4 days), with 57.1% undergoing surgery >24 hours later. Localization success rate was 100%. CT-guided transthoracic placement of ICG-C is a novel technique that allows for accurate nodule localization, delayed surgical resection, and the preservation of healthy lung tissue.

摘要

使用微创技术进行肺结节切除的胸外科医生通常依靠定位标记物在术中确定结节的精确位置。经支气管或经胸注射吲哚菁绿（ICG）染料已成为一种常用技术。然而，手术必须在染料扩散到周围组织之前立即进行。这项多中心回顾性研究评估了计算机断层扫描（CT）引导下经胸放置ICG染料浸泡线圈（ICG-Cs）用于术前肺结节定位的有效性。2023年3月1日至2025年2月28日期间，在2个医疗中心，19例成年患者的21个结节接受了CT引导下的ICG-C放置。未发生不良事件。从定位到手术的中位时间为1天（四分位间距，0-4天），57.1%的患者在24小时后接受手术。定位成功率为100%。CT引导下经胸放置ICG-C是一种新技术，可实现准确的结节定位、延迟手术切除并保留健康肺组织。