Ol'khovskaia I G
Arkh Patol. 1985;47(11):20-5.
Epithelium alterations such as hyperplasia of goblet and basal cells, transitional-cell and/or squamous-cell metaplasia with cell polymorphism, disturbance of stratification are revealed in the bronchial biopsies and bronchi of the lungs surgically removed for cancer; these alterations are interpreted as dysplasia of bronchial epithelium. The foci of intra-epithelial carcinoma were also found. Dysplastic changes of bronchial epithelium should be regarded as a factor increasing the risk of lung cancer.
在因癌症而手术切除的肺脏的支气管活检组织和支气管中，发现了上皮细胞改变，如杯状细胞和基底细胞增生、具有细胞多形性的移行细胞和/或鳞状细胞化生、分层紊乱；这些改变被解释为支气管上皮发育异常。还发现了上皮内癌灶。支气管上皮的发育异常改变应被视为增加肺癌风险的一个因素。
