Merritt Sean H
St. Luke's Health System, Boise, Idaho, USA.
J Eval Clin Pract. 2025 Sep;31(6):e70259. doi: 10.1111/jep.70259.
Voucher-based food as medicine programs have become a common method to help reduce the burden of chronic disease. While recent studies find these programs reduce HbA1c, few of these studies included a comparison group.
This article evaluates the impact of a clinically based voucher program on HbA1c of diabetic patients.
This study takes advantage of a natural experiment to create a robust control group. Individuals with diabetes or prediabetes were screened for food insecurity to enroll in the program. If a person enrolled, they would receive a voucher for fruits and vegetables at select stores for 6 months (N = 389). During a period of transition between voucher delivery methods, participants were put on a waiting list rather than enrolling. These individuals were identified as part of the control group (N = 36). Electronic medical record data was used to link individuals pre- and post-HbA1c. Inverse propensity score weighting (IPW) and nearest neighbor (NN) matching were used to determine treatment effects.
After removing patients who did not have post-A1c measurements, there were 140 people included (treated = 120; control = 20). There was not found to be a statistically significant impact of voucher programs on HbA1c using IPW (b = 0.16, p = 0.659) or NN (b = 0.35, p = 0.071). Power analysis finds that this analysis was likely underpowered given the small effect size.
These results suggest that voucher programs may not be as effective at reducing HbA1c of diabetes patients as previously thought. However, there may be additional barriers that these kinds of programs may not be addressing. The author makes recommendations for how to rethink the focus of diabetes interventions for those with food insecurity.
基于代金券的“食物即药物”项目已成为帮助减轻慢性病负担的常用方法。尽管最近的研究发现这些项目能降低糖化血红蛋白(HbA1c),但这些研究中很少有设置对照组的。
本文评估一项基于临床的代金券项目对糖尿病患者糖化血红蛋白的影响。
本研究利用一项自然实验来创建一个有力的对照组。对患有糖尿病或糖尿病前期的个体进行粮食不安全筛查,以纳入该项目。如果一个人登记参加,他们将在指定商店获得为期6个月的水果和蔬菜代金券(N = 389)。在代金券发放方式的过渡期间,参与者被列入等候名单而不是登记参加。这些个体被确定为对照组的一部分(N = 36)。利用电子病历数据将个体糖化血红蛋白前后的数据进行关联。采用逆倾向评分加权法(IPW)和最近邻匹配法(NN)来确定治疗效果。
在剔除没有糖化血红蛋白后期测量值的患者后,纳入了140人(治疗组 = 120;对照组 = 20)。使用IPW(b = 0.16,p = 0.659)或NN(b = 0.35,p = 0.071)方法未发现代金券项目对糖化血红蛋白有统计学上的显著影响。功效分析发现,鉴于效应量较小,该分析可能功效不足。
这些结果表明,代金券项目在降低糖尿病患者糖化血红蛋白方面可能不如之前认为的那么有效。然而,这类项目可能没有解决其他一些障碍。作者就如何重新思考针对粮食不安全人群的糖尿病干预重点提出了建议。