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慢性胰腺炎中的胰胃瘘:复发性大量上消化道出血的一种罕见且危及生命的病因。

Pancreatogastric fistula in chronic pancreatitis: a rare and life-threatening cause of recurrent massive upper gastrointestinal bleeding.

作者信息

Wijerathne Sanduni, Bandaranayake Gayathri, Abeysinghe Anjana, Sivaganesh Sivasuriya, Fernandopulle Nilesh, Subasinghe Duminda

机构信息

Department of Surgery, Faculty of Medicine, University of Colombo, No. 25, Kynsey Road, Colombo 8, Sri Lanka.

University Surgical Unit, The National Hospital of Sri Lanka, Colombo 10, Sri Lanka.

出版信息

J Surg Case Rep. 2025 Sep 6;2025(9):rjaf619. doi: 10.1093/jscr/rjaf619. eCollection 2025 Sep.

Abstract

Pancreatogastric fistulas are rare but serious complications of chronic pancreatitis that can lead to life-threatening gastrointestinal bleeding due to erosion of nearby blood vessels. We present a case of a 43-year-old man with chronic calcific pancreatitis and a history of alcohol misuse, who experienced recurrent hematemesis and melena over 2 months. Despite multiple endoscopies and transfusions, the bleeding source remained unidentified until imaging revealed a fistulous tract between the pancreas and the posterior gastric wall. After failed endoscopic control, surgery confirmed the fistula and bleeding vessel, which were managed with vessel ligation and gastric resection. This case underscores the need to consider pancreatogastric fistulas in patients with chronic pancreatitis and unexplained gastrointestinal bleeding, particularly when standard investigations are inconclusive and conservative measures fail.

摘要

胰胃瘘是慢性胰腺炎罕见但严重的并发症,由于附近血管受侵蚀可导致危及生命的胃肠道出血。我们报告一例43岁男性慢性钙化性胰腺炎患者,有酒精滥用史,在2个月内反复出现呕血和黑便。尽管进行了多次内镜检查和输血,但出血源一直未明确,直到影像学检查显示胰腺与胃后壁之间存在瘘管。在内镜控制失败后,手术证实了瘘管和出血血管,通过血管结扎和胃切除术进行了处理。该病例强调,对于慢性胰腺炎和不明原因胃肠道出血的患者,尤其是当标准检查无定论且保守措施失败时,需要考虑胰胃瘘的可能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8251/12413757/21b148b0c1a6/rjaf619f1.jpg

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