Fukuda Kazuhiro, Kotoda Satoru, Fukaya Kaori, Yokota Eisuke, Yamasaki Shigetaka, Horie Shigeo
Department of Urology, Koshigaya Municipal Hospital, Koshigaya, Saitama, Japan.
Department of Pathology, Tokyo Rinkai Hospital, Tokyo, Japan.
Res Rep Urol. 2025 Sep 1;17:321-326. doi: 10.2147/RRU.S532738. eCollection 2025.
Non-epithelial bladder neoplasms are rare, and there are only approximately 250 cases of bladder leiomyoma reported in the English literature. We present a case of bladder leiomyoma in a patient with recurrent acute cystitis.
A 53-year-old woman presented to a local clinic with frequent urination and dysuria and was diagnosed with acute cystitis. Her symptoms temporarily improved after taking oral antibiotics, but then flared up repeatedly. Contrast-enhanced computed tomography showed a bladder neck leiomyoma and multiple uterine fibroids. Her body mass index was 27.0 kg/m. The patient successfully underwent transurethral resection of the tumor. The histopathological diagnosis was bladder leiomyoma.
There have been few cases of bladder leiomyoma coexisting with urinary tract infection and uterine fibroids. Our findings suggest that female hormones, which might increase body weight and cause fatty liver, are associated with the growth of bladder leiomyomas. If a patient has recurrent urinary tract infection, a bladder leiomyoma should be included in the differential diagnoses.
非上皮性膀胱肿瘤较为罕见，英文文献中仅报道了约250例膀胱平滑肌瘤病例。我们报告一例患有复发性急性膀胱炎的膀胱平滑肌瘤患者。
一名53岁女性因尿频和尿痛就诊于当地诊所，被诊断为急性膀胱炎。口服抗生素后其症状暂时改善，但随后反复发作。增强计算机断层扫描显示膀胱颈部平滑肌瘤和多个子宫肌瘤。她的体重指数为27.0kg/m²。患者成功接受了经尿道肿瘤切除术。组织病理学诊断为膀胱平滑肌瘤。
膀胱平滑肌瘤合并尿路感染和子宫肌瘤的病例很少见。我们的研究结果表明，可能会增加体重并导致脂肪肝的女性激素与膀胱平滑肌瘤的生长有关。如果患者有复发性尿路感染，鉴别诊断中应考虑膀胱平滑肌瘤。
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