文献检索
文档翻译
深度研究
学术资讯

Zotero 插件

邀请有礼
套餐&价格
历史记录

应用&插件

Zotero 插件浏览器插件 Mac 客户端 Windows 客户端微信小程序

定价

高级版会员购买积分包购买API积分包

服务

文献检索文档翻译深度研究 API 文档 MCP 服务

关于我们

关于 Suppr 公司介绍联系我们用户协议隐私条款

关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

某些5-取代的5H-(1)苯并吡喃并(4,3-b)吡啶的合成及正性肌力作用

[Synthesis and positive inotropic action of some 5-substituted 5H-(1)benzopyrano(4,3-b)pyridines].

作者信息

Heber D, Ravens U

出版信息

Arzneimittelforschung. 1985;35(11):1624-6.

Abstract

The 5-hydroxy-5H-[1]benzopyrano [4,3-b]pyridines (4) were converted to the acetales 7-10 on treatment with alcoholic solutions in the presence of concentrated hydrochloric acid. Reactions of with aliphatic and aromatic amines yielded the aminoacetales 11-15. The effects of compounds 7-15 were examined on the isolated perfused guinea-pig heart.

摘要

5-羟基-5H-[1]苯并吡喃并[4,3-b]吡啶（4）在浓盐酸存在下用醇溶液处理后转化为缩醛7-10。其与脂肪族和芳香族胺反应生成氨基缩醛11-15。研究了化合物7-15对离体灌注豚鼠心脏的作用。

相似文献

1

[Synthesis and positive inotropic action of some 5-substituted 5H-(1)benzopyrano(4,3-b)pyridines].某些5-取代的5H-(1)苯并吡喃并(4,3-b)吡啶的合成及正性肌力作用

Arzneimittelforschung. 1985;35(11):1624-6.

2

Synthesis and positive inotropic activity of several 5-aminopyrido[2,3-d]pyrimidines. Part 5: Compounds with positive inotropic activity.几种5-氨基吡啶并[2,3-d]嘧啶的合成及正性肌力活性。第5部分：具有正性肌力活性的化合物。

Pharmazie. 1993 Jul;48(7):509-13.

3

[Potential cardiotonics. 7. Synthesis and cardiovascular effects of 5-(4-pyridinyl)-, 6-methyl-4-(4-pyridinyl) and 6-methyl-5-phenyl-substituted 3-cyano-2-aminoalkylamino-pyridines].[潜在强心剂。7. 5-(4-吡啶基)-、6-甲基-4-(4-吡啶基)和6-甲基-5-苯基取代的3-氰基-2-氨基烷基氨基吡啶的合成及心血管效应]

Pharmazie. 1990 Apr;45(4):240-1.

4

[Potential cardiotonics. 9. Synthesis and cardiovascular effects of 2-(pyrid-3-yl)-methylamino-, 2-(3-amino-pyrazolidino)- and 2-hetarylamino-substituted 3-cyan-5-(pyrid-4-yl)-pyridines].[潜在强心剂。9. 2-(吡啶-3-基)-甲氨基、2-(3-氨基-吡唑烷基)和2-杂芳基氨基取代的3-氰基-5-(吡啶-4-基)-吡啶的合成及心血管效应]

Pharmazie. 1989 Dec;44(12):859-60.

5

[Potential cardiotonic agents. 10. Synthesis and positive inotropic action of 5-(4-pyridinyl)- and 5-phenyl-substituted 2-alkylthio-3-cyan-pyridines and their S-oxidation products].[潜在强心剂。10. 5-(4-吡啶基)-和5-苯基取代的2-烷硫基-3-氰基吡啶及其S-氧化产物的合成与正性肌力作用]

Pharmazie. 1990 Sep;45(9):657-9.

6

[Potential cardiotonic agents. 1. Synthesis and pharmacologic properties of 3-cyano-2-oxaalkylamino-5-(4-pyridinyl)pyridines].[潜在的强心剂。1. 3-氰基-2-氧杂烷基氨基-5-(4-吡啶基)吡啶的合成及药理性质]

Pharmazie. 1989 Jan;44(1):20-3.

7

[Synthesis of 5H [1]benzopyrano[2,3-b] pyridine derivatives].[5H [1]苯并吡喃并[2,3 - b]吡啶衍生物的合成]

Acta Pol Pharm. 1977;34(1):1-7.

8

[Synthesis and cardiotonic activity of pyrazolylpyrimidines].[吡唑基嘧啶的合成及其强心活性]

Pharmazie. 1998 Apr;53(4):233-7.

9

[Potential cardiotonic agents. 6. Synthesis and cardiovascular properties of 5-(4-pyridinyl)-, 6-methyl-5-(4-pyridinyl)- and 6-methyl-5-phenyl-substituted 3-cyano-2-oxaalkyoxy-pyridines].[潜在强心剂。6. 5-(4-吡啶基)-、6-甲基-5-(4-吡啶基)-和6-甲基-5-苯基取代的3-氰基-2-氧杂烷氧基吡啶的合成及心血管性质]

Pharmazie. 1990 Mar;45(3):189-90.

10

[Potential cardiotonic agents. 4. Synthesis, cardiovascular activity, molecular and crystal structure of 5-phenyl- and 4-(4-pyridinyl)-substituted 2(1H)-pyridinethiones].[潜在强心剂。4. 5-苯基和4-(4-吡啶基)取代的2(1H)-吡啶硫酮的合成、心血管活性、分子结构和晶体结构]

Pharmazie. 1989 Dec;44(12):809-13.