Kassab Joseph, Hajj Joseph, Puri Rishi, Yun James, Reed Grant, Krishnaswamy Amar, Harb Serge C, Kapadia Samir R
Division of Cardiovascular Medicine, Department of Internal Medicine, UT Southwestern Medical Center, Dallas, Texas, USA.
Heart and Vascular Institute, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA.
Struct Heart. 2025 Jul 29;9(9):100709. doi: 10.1016/j.shj.2025.100709. eCollection 2025 Sep.
•Outcomes of surgical aortic valve replacement + coronary artery bypass grafting vs. transcatheter aortic valve replacement (TAVR) + percutaneous coronary intervention (PCI) in severe aortic stenosis and coronary artery disease patients.•TAVR + PCI had lower 30-day acute kidney injury and bleeding, similar 2-year mortality/stroke.•PCI timing (pre-, peri-, and post-TAVR) did not impact long-term clinical outcomes.•Results support TAVR + PCI as a viable option in select high-risk patients.
• 严重主动脉瓣狭窄合并冠状动脉疾病患者接受外科主动脉瓣置换术+冠状动脉搭桥术与经导管主动脉瓣置换术（TAVR）+经皮冠状动脉介入治疗（PCI）的疗效比较。
• TAVR+PCI组30天急性肾损伤和出血发生率较低，2年死亡率/中风发生率相似。
• PCI时机（TAVR前、围手术期和术后）不影响长期临床结局。
• 结果支持TAVR+PCI作为特定高危患者的可行选择。
