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伪装成颅内低压的慢性硬膜下血肿

Chronic Subdural Hematoma Masquerading as Intracranial Hypotension.

作者信息

Sharkey Brandon, Lucarelli Vito, Kosco Ethan, Mendonsa Maya, Lawrence Austin, Reinard Kevin

机构信息

Department of Neurological Surgery, University of Toledo College of Medicine and Life Sciences, Toledo, USA.

Department of Neurological Surgery, ProMedica Toledo Hospital, Toledo, USA.

出版信息

Cureus. 2025 Aug 5;17(8):e89431. doi: 10.7759/cureus.89431. eCollection 2025 Aug.

Abstract

Spontaneous intracranial hypotension (SIH) is caused by cerebrospinal fluid leak and has an incidence of approximately five per 100,000 person-years. SIH leads to a range of clinical symptoms, from debilitating postural headaches to subdural hematomas (SDHs). The pathophysiology of the disease is not fully understood, but has garnered interest in recent years. Although CT myelogram and pan-spine MRIs are currently considered the gold standard for diagnosis of SIH, the variable sensitivity (48-76%) and wide range of hematoma size (2-30 mm) warrant further investigation into improved diagnostic and treatment options. We present the case of a patient with non-traumatic bilateral SDHs and clinical findings suggestive of intracranial hypotension and CSF leak. The patient initially presented with typical signs and symptoms of SIH and resulting SDH. However, her clinical course was highly unusual given the sudden resolution of her symptoms despite receiving interventions that were not believed to have repaired the underlying pathology. This unique presentation of an SDH encourages the need for larger prospective studies of patients with SIH and SDH and the exploration of the role and efficacy of middle meningeal artery (MMA) embolization. This procedure is a new and promising treatment for SDH regardless of the etiology.

摘要

自发性颅内低压(SIH)由脑脊液漏引起,发病率约为每10万人年5例。SIH会导致一系列临床症状,从使人衰弱的体位性头痛到硬膜下血肿(SDH)。该疾病的病理生理学尚未完全了解,但近年来已引起关注。尽管目前CT脊髓造影和全脊柱磁共振成像被认为是诊断SIH的金标准,但可变的敏感性(48 - 76%)和血肿大小范围广(2 - 30毫米)使得有必要进一步研究改进诊断和治疗方案。我们报告一例非创伤性双侧SDH患者的病例,其临床表现提示颅内低压和脑脊液漏。患者最初表现出SIH及由此导致的SDH的典型体征和症状。然而,尽管接受了被认为未修复潜在病理状况的干预措施,但其症状却突然缓解,其临床病程非常不寻常。这种独特的SDH表现促使有必要对SIH和SDH患者进行更大规模的前瞻性研究,并探索脑膜中动脉(MMA)栓塞的作用和疗效。无论病因如何,该手术都是一种新的、有前景的SDH治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41c8/12410595/aba33e3d2bff/cureus-0017-00000089431-i01.jpg

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