Managing Laryngeal Carcinoma in the United Arab Emirates: An Experience From the Tertiary Care Center.

Background Laryngeal cancer is a common head and neck malignancy. The treatment modalities differ depending on the clinical staging and location of the tumor, hence affecting the survival outcomes. Objective This study aims to provide demographic information and survival outcomes in laryngeal cancer patients in the UAE, considering the clinical staging and treatment received. Methods A retrospective cohort study in laryngeal cancer patients at Tawam Hospital from 2016 to 2020. Descriptive analysis summarized the demographics and survival analysis using Kaplan-Meier curves, comparing outcomes between early and advanced stages, as well as treatment modality (surgical vs non-surgical). We also used the log-rank test to assess statistical significance. Results A total of 63 patients were included in the study. Patients with early-stage disease showed better survival in the surgical compared to the non-surgical primary treatment. On the contrary, patients with advanced-stage disease had better survival outcomes in the non-surgical treatment group than in the surgical group. Conclusion Compared to early-stage disease, the treatment modality does affect the survival outcomes in advanced stages. These results suggest a potential benefit favoring the non-surgical treatment modality, but further prospective studies with larger sample sizes are needed.