Aldhaheri Reem, Ansari Shayan, Alkatheeri Rana, Alshamsi Mariam, Alhajeri Latifa, Alghafri Ameera
Otolaryngology, Tawam Hospital, Al Ain, ARE.
Cureus. 2025 Aug 7;17(8):e89563. doi: 10.7759/cureus.89563. eCollection 2025 Aug.
Background Laryngeal cancer is a common head and neck malignancy. The treatment modalities differ depending on the clinical staging and location of the tumor, hence affecting the survival outcomes. Objective This study aims to provide demographic information and survival outcomes in laryngeal cancer patients in the UAE, considering the clinical staging and treatment received. Methods A retrospective cohort study in laryngeal cancer patients at Tawam Hospital from 2016 to 2020. Descriptive analysis summarized the demographics and survival analysis using Kaplan-Meier curves, comparing outcomes between early and advanced stages, as well as treatment modality (surgical vs non-surgical). We also used the log-rank test to assess statistical significance. Results A total of 63 patients were included in the study. Patients with early-stage disease showed better survival in the surgical compared to the non-surgical primary treatment. On the contrary, patients with advanced-stage disease had better survival outcomes in the non-surgical treatment group than in the surgical group. Conclusion Compared to early-stage disease, the treatment modality does affect the survival outcomes in advanced stages. These results suggest a potential benefit favoring the non-surgical treatment modality, but further prospective studies with larger sample sizes are needed.
喉癌是一种常见的头颈部恶性肿瘤。治疗方式因肿瘤的临床分期和位置而异，从而影响生存结果。
本研究旨在提供阿联酋喉癌患者的人口统计学信息和生存结果，同时考虑临床分期和接受的治疗。
对2016年至2020年在塔瓦姆医院的喉癌患者进行一项回顾性队列研究。描述性分析总结了人口统计学数据，并使用Kaplan-Meier曲线进行生存分析，比较早期和晚期阶段以及治疗方式（手术与非手术）之间的结果。我们还使用对数秩检验来评估统计学意义。
共有63名患者纳入研究。早期疾病患者在手术治疗与非手术主要治疗相比，显示出更好的生存率。相反，晚期疾病患者在非手术治疗组中的生存结果优于手术组。
与早期疾病相比，治疗方式确实会影响晚期的生存结果。这些结果表明非手术治疗方式可能具有潜在益处，但需要进一步进行更大样本量的前瞻性研究。
