Aziz Ajwa Tariq, Shabbir Sidra, Bashir Hifza, Iqbal Aqsa, Tufail Aneeza, Yousaf Marya, Abdullah Muhammad, Fatima Nizam, Sikandar Mirza Zeeshan
General Surgery, Rashid Latif Medical College, Lahore, PAK.
General Surgery, Rahbar Medical and Dental College, Lahore, PAK.
Cureus. 2025 Aug 5;17(8):e89414. doi: 10.7759/cureus.89414. eCollection 2025 Aug.
Fistula-in-ano is a relatively common benign disease of the anorectal region, which may pose considerable complications in terms of surgery, as this disease has the propensity to recur and may be accompanied by postoperative wound healing. Surgical therapy can be considered the key in the management, and surgery involves fistulectomy or fistulotomy as a part of surgical treatment. Nevertheless, due to the fear of slow healing of the wound and acquiring infection because of common methods, some other methods have been explored, and some have been suggested to be defined as the process of marsupialization, which could allow decreasing the size of the open wound and stimulate its recovery quicker.
To compare the incidence of postoperative wound infection between fistulectomy alone and fistulotomy with marsupialization in patients with low anal fistula.
MATERIALS & METHODS: The study(randomized controlled trial) was done in Arif Memorial Teaching Hospital and Central Park Medical College, Lahore, from January to September 2024. Low fistula-in-ano patients were randomized into two groups, i.e., Group A (SUR one fistulectomy) and Group B (170 patients in each group). The same surgical team applied all their procedures to reach spinal anesthesia. Wound infection was determined after the operation was done clinically and verified by culture at 10 days of follow-up. Statistical analyses based on SPSS version 26 were carried out, and p < 0.05 was considered significant.
Average age of sample population was 36.3, 12.2 years, with males prevailing (80.9 %). Baseline data were similar between the two groups. All in all, there were 58 patients (17.1%) who had wound infections after the operation. Group B (fistulotomy with marsupialization) resulted in a much lower wound infection rate (10.0%) as compared with group A (24.1%) (p=0.001). The findings presented in subgroup analyses indicated that the benefit of marsupialization was consistent across all age, gender, fistula type, and duration of the disease, with the majority of the differences being statistically significant.
Fistulotomy and marsupialization showed a considerably reduced postoperative wound infection rate compared to the conventional fistulectomy in patients with low fistula-in-ano.
肛瘘是肛肠区域一种相对常见的良性疾病,在手术方面可能会引发相当多的并发症,因为这种疾病容易复发,且术后伤口愈合可能会受到影响。手术治疗可被视为管理的关键,手术包括瘘管切除术或瘘管切开术作为手术治疗的一部分。然而,由于担心常用方法导致伤口愈合缓慢和感染,人们探索了一些其他方法,其中一些被建议定义为袋形缝合术,这可以减小开放伤口的大小并更快地促进其恢复。
比较单纯瘘管切除术与袋形缝合瘘管切开术在低位肛瘘患者术后伤口感染的发生率。
该研究(随机对照试验)于2024年1月至9月在拉合尔的阿里夫纪念教学医院和中央公园医学院进行。低位肛瘘患者被随机分为两组,即A组(单纯瘘管切除术)和B组(每组170例患者)。同一手术团队采用所有手术步骤,均采用脊髓麻醉。术后通过临床检查确定伤口感染情况,并在随访10天时通过培养进行验证。基于SPSS 26版进行统计分析,p<0.05被认为具有统计学意义。
样本人群的平均年龄为36.3岁,标准差为12.2岁,男性占主导(80.9%)。两组的基线数据相似。总体而言,有58例患者(17.1%)术后出现伤口感染。与A组(24.1%)相比,B组(袋形缝合瘘管切开术)的伤口感染率要低得多(10.0%)(p=0.001)。亚组分析结果表明,袋形缝合术的益处适用于所有年龄、性别、瘘管类型和病程,大多数差异具有统计学意义。
对于低位肛瘘患者,与传统的瘘管切除术相比,瘘管切开术和袋形缝合术术后伤口感染率显著降低。