Kawamura M, Yagishita T, Kojima S, Hirayama K, Soma Y, Arimizu N
No To Shinkei. 1985 Dec;37(12):1203-10.
The recent use of computed tomography (CT) scan is providing an easy diagnoses of agenesis of corpus callosum which had been difficult to diagnose only by clinical signs and symptoms. Since, more neuropsychological studies on agenesis of corpus callosum are being done, clinical details of agenesis of corpus callosum are being clarified. We examined magnetic resonance imaging (MRI) on 3 patients who were suspected to have agenesis of corpus callosum by CT scan. And we studied the usefulness of MRI in agenesis of corpus callosum. Case 1. We studied a thirty-two-year-old right-handed man with a one-year history of amyotrophic lateral sclerosis. He had no callosal disconnection syndrome. CT scan on horizontal view showed dilated third ventricle, the dilatation of the occipital horns and wide separation of the lateral ventricles. On coronal view, CT scan showed the absence of the corpus callosum, the concave mesial borders of the lateral ventricle, the dilatation of the third ventricle and its abnormal dorsal extent(bat-wing appearance). On sagittal MRI (the inversion recovery technique), the corpus callosum was absent and the convolutions and sulci were arranged radically centering the third ventricle (radial distribution). But the anterior commissure was preserved. Case 2. We studied a fourty-one-year-old right-handed man with a seven-year history of hyper ventilation syndrome. He had no callosal disconnection syndrome. CT scan showed the similar findings as those of case 1. On sagittal MRI (the inversion recovery technique), the corpus callosum was absent, and the convolutions and sulci showed radial distribution. But the anterior commissure was preserved.(ABSTRACT TRUNCATED AT 250 WORDS)
近期计算机断层扫描(CT)的应用使得胼胝体发育不全的诊断变得容易,而仅通过临床体征和症状很难诊断该病。由于对胼胝体发育不全开展了更多神经心理学研究,胼胝体发育不全的临床细节正逐渐明晰。我们对3例经CT扫描怀疑患有胼胝体发育不全的患者进行了磁共振成像(MRI)检查。我们研究了MRI在胼胝体发育不全诊断中的作用。病例1。我们研究了一名32岁的右利手男性,他有1年肌萎缩侧索硬化病史。他没有胼胝体分离综合征。水平位CT扫描显示第三脑室扩张、枕角扩张以及侧脑室间距增宽。冠状位CT扫描显示胼胝体缺失、侧脑室内侧缘凹陷、第三脑室扩张及其异常的背侧范围(蝙蝠翼样外观)。矢状位MRI(反转恢复技术)显示胼胝体缺失,脑回和脑沟以第三脑室为中心呈放射状排列(放射状分布)。但前连合保留。病例2。我们研究了一名41岁的右利手男性,他有7年的过度通气综合征病史。他没有胼胝体分离综合征。CT扫描显示与病例1相似的结果。矢状位MRI(反转恢复技术)显示胼胝体缺失,脑回和脑沟呈放射状分布。但前连合保留。(摘要截断于250字)