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Studies on the chemical constituents of rutaceous plants. LX. Development of a versatile method for syntheses of the antitumor benzo[c]phenanthridine alkaloids. (9). Efficient syntheses and antitumor activities of nitidine and related nonphenolic benzo[c]phenanthridine alkaloids.

作者信息

Ishii H, Ichikawa Y, Kawanabe E, Ishikawa M, Ishikawa T, Kuretani K, Inomata M, Hoshi A

出版信息

Chem Pharm Bull (Tokyo). 1985 Oct;33(10):4139-51. doi: 10.1248/cpb.33.4139.

DOI:10.1248/cpb.33.4139
PMID:4092262
Abstract
摘要

相似文献

1
Studies on the chemical constituents of rutaceous plants. LX. Development of a versatile method for syntheses of the antitumor benzo[c]phenanthridine alkaloids. (9). Efficient syntheses and antitumor activities of nitidine and related nonphenolic benzo[c]phenanthridine alkaloids.芸香科植物化学成分的研究。LX. 一种通用的抗肿瘤苯并[c]菲啶生物碱合成方法的开发。(9). 氧化苦参碱及相关非酚性苯并[c]菲啶生物碱的高效合成与抗肿瘤活性。
Chem Pharm Bull (Tokyo). 1985 Oct;33(10):4139-51. doi: 10.1248/cpb.33.4139.
2
Studies on the chemical constituents of rutaceous plants. LVI. The development of a versatile method for the synthesis of antitumor-active benzo[c]phenanthridine alkaloids. (6). Limitation of the Dyke synthetic pathway for benzo[c]phenanthridine alkaloids.芸香科植物的化学成分研究。第五十六部分。一种用于合成具有抗肿瘤活性的苯并[c]菲啶生物碱的通用方法的开发。（6）。苯并[c]菲啶生物碱的戴克合成途径的局限性。
Chem Pharm Bull (Tokyo). 1984 Aug;32(8):3248-51. doi: 10.1248/cpb.32.3248.
3
Studies on the chemical constituents of Rutaceous plants. LV. The development of a versatile method for the synthesis of antitumor-active benzo[c]phenanthridine alkaloids. (5). A new method for quaternization of the benzo[c]phenanthridine nucleus.芸香科植物化学成分的研究。第五部分。一种通用的合成抗肿瘤活性苯并[c]菲啶生物碱方法的进展。（5）。苯并[c]菲啶环季铵化的新方法。
Chem Pharm Bull (Tokyo). 1984 Aug;32(8):2984-94. doi: 10.1248/cpb.32.2984.
4
Studies on the chemical constituents of Rutaceous plants. LIV. The development of a versatile method for the synthesis of antitumor-active benzo[c]phenanthridine alkaloids. (4). Limitation of Bischler-Napieralski cyclization and detailed examination of the dehydrogenation of the Bischler-Napieralski products in the Robinson synthetic pathway for benzo[c]phenanthridine alkaloids.芸香科植物的化学成分研究。第四部分。一种合成抗肿瘤活性苯并[c]菲啶生物碱通用方法的开发。(4). 苯并[c]菲啶生物碱罗宾逊合成途径中Bischler-Napieralski环化反应的局限性及对Bischler-Napieralski产物脱氢反应的详细研究。
Chem Pharm Bull (Tokyo). 1984 Aug;32(8):2971-83. doi: 10.1248/cpb.32.2971.
5
[Chemistry of benzo[c]phenanthridine alkaloids having antineoplastic activity (author's transl)].具有抗肿瘤活性的苯并[c]菲啶生物碱的化学（作者译）
Yakugaku Zasshi. 1981 Aug;101(8):663-87. doi: 10.1248/yakushi1947.101.8_663.
6
Synthesis and cytotoxic activities of a new benzo[c]phenanthridine alkaloid, 7-hydroxynitidine, and some 9-oxygenated benzo[c]phenanthridine derivatives.一种新型苯并[c]菲啶生物碱7-羟基氯化两面针碱及一些9-氧化苯并[c]菲啶衍生物的合成与细胞毒活性
Org Lett. 1999 Oct 7;1(7):985-8. doi: 10.1021/ol990775g.
7
Total synthesis of oxyfagaronine, phenolic benzo[c]phenanthridine and general synthetic way of 2,3,7,8- and 2,3,8,9-tetrasubstituted benzo[c]phenanthridine alkaloids.氧化法卡林碱的全合成、酚性苯并[c]菲啶以及2,3,7,8-和2,3,8,9-四取代苯并[c]菲啶生物碱的通用合成方法。
Chem Pharm Bull (Tokyo). 2006 Apr;54(4):476-80. doi: 10.1248/cpb.54.476.
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Substituted benzo[i]phenanthridines as mammalian topoisomerase-targeting agents.作为哺乳动物拓扑异构酶靶向剂的取代苯并[i]菲啶
Bioorg Med Chem. 2003 Apr 17;11(8):1809-20. doi: 10.1016/s0968-0896(03)00053-1.
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Synthesis and evaluation of new 6-amino-substituted benzo[c]phenanthridine derivatives.新型6-氨基取代苯并[c]菲啶衍生物的合成与评价
J Med Chem. 1993 Nov 12;36(23):3686-92. doi: 10.1021/jm00075a025.
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Synthesis and cytotoxic activity of benzo[c][1,7] and [1,8]phenanthrolines analogues of nitidine and fagaronine.两面针碱和白屈菜红碱的苯并[c][1,7]和[1,8]菲咯啉类似物的合成及其细胞毒性活性
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