Chen Bichi, Lin Na, Tian Li, Mao Jieli, Yang Maoyuan, Sun Xueqin, Lu Fan, Deng Ruzhi
National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, People's Republic of China.
Eye Brain. 2025 Sep 3;17:115-124. doi: 10.2147/EB.S533112. eCollection 2025.
To investigate the impact of mild visual acuity loss on the Müller-Lyer illusion in adults and evaluate its potential as a clinical indicator for visual-cognitive integration mechanisms.
Three experiments were conducted. Experiment 1 measured illusion intensity in 49 young adults (25.08 ± 3.38 years) before and after inducing transient visual acuity loss (0.40 logMAR) via Bangerter occlusion foils. Experiment 2 compared 26 cataract patients (65.19 ± 3.87 years) with 59 age-matched controls (63.98 ± 5.57 years). Experiment 3 tracked 14 cataract patients (69.50 ± 6.14 years) pre- and post-surgery. Illusion intensity was quantified using a two-alternative forced-choice task.
Illusion intensity remained stable across conditions: no differences were observed before /after wearing occlusion glasses (4.33% vs 3.75%, = 0.141), between cataract patients and controls (8.79% vs 8.20%, = 0.301), or pre-/post-surgery (9.46% vs 9.87%, = 0.357). However, normally-sighted elderly participants exhibited stronger illusions than young adults (8.20% vs 4.33%, < 0.001). Multivariate regression confirmed age as the sole predictor of illusion intensity ( = 0.088, = 0.001), independent of visual acuity.
The intensity of Müller-Lyer illusion in adults is modulated by age but resistant to mild visual acuity loss, implicating its utility in studying visual-cognitive integration.
研究轻度视力丧失对成年人缪勒-莱尔错觉的影响，并评估其作为视觉认知整合机制临床指标的潜力。
进行了三项实验。实验1通过班格特遮挡箔片诱导49名年轻成年人（25.08±3.38岁）暂时视力丧失（0.40 logMAR）前后测量错觉强度。实验2比较了26名白内障患者（65.19±3.87岁）和59名年龄匹配的对照组（63.98±5.57岁）。实验3追踪了14名白内障患者（69.50±6.14岁）手术前后的情况。使用二项选择强迫选择任务量化错觉强度。
错觉强度在各种条件下保持稳定：佩戴遮挡眼镜前后未观察到差异（4.33%对3.75%，P = 0.141），白内障患者与对照组之间无差异（8.79%对8.20%，P = 0.301），手术前后也无差异（9.46%对9.87%，P = 0.357）。然而，视力正常的老年参与者比年轻成年人表现出更强的错觉（8.20%对4.33%，P < 0.001）。多变量回归证实年龄是错觉强度的唯一预测因素（β = 0.088，P = 0.001），与视力无关。
成年人缪勒-莱尔错觉的强度受年龄调节，但对轻度视力丧失具有抗性，这表明其在研究视觉认知整合方面的实用性。
