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特应性皮炎中的心血管合并症:关于度普利尤单抗对皮肤和心脏功能影响的病例报告

Cardiovascular Comorbidities in Atopic Dermatitis: A Case Report on the Impact of Dupilumab on Skin and Heart Function.

作者信息

Gluszak Pawel, Wazniewicz Sandra, Chmielewska-Michalak Lidia, Kandola Pervana, Jenerowicz Dorota

机构信息

Department of Dermatology, Poznan University of Medical Sciences, Poznan, POL.

Department of Cardiology, Poznan University of Medical Sciences, Poznan, POL.

出版信息

Cureus. 2025 Aug 7;17(8):e89586. doi: 10.7759/cureus.89586. eCollection 2025 Aug.

Abstract

Atopic dermatitis (AD) is a chronic inflammatory skin condition often complicated by cardiovascular comorbidities, impacting treatment options and outcomes. In this paper, we present a 41-year-old patient with severe AD, asthma, and chronic heart failure, who responded well to dupilumab, showing significant improvements in skin severity scores and heart function. This case underscores the effectiveness of dupilumab in managing AD alongside complex comorbidities.

摘要

特应性皮炎(AD)是一种慢性炎症性皮肤病,常伴有心血管合并症,影响治疗选择和治疗效果。在本文中,我们介绍了一名41岁患有重度特应性皮炎、哮喘和慢性心力衰竭的患者,该患者对度普利尤单抗反应良好,皮肤严重程度评分和心脏功能有显著改善。该病例强调了度普利尤单抗在治疗伴有复杂合并症的特应性皮炎方面的有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e98d/12414131/0ed6e784483d/cureus-0017-00000089586-i01.jpg

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