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静脉血栓栓塞风险评估与预防:一项基于审计的研究。

Venous Thromboembolism Risk Assessment and Prophylaxis: An Audit-Based Study.

作者信息

Akhtar Asfia N, Hameed Faizan, O'Shea Susan

机构信息

Respiratory Medicine, University Hospital Waterford, Waterford, IRL.

Internal Medicine, Bon Secours Hospital, Cork, IRL.

出版信息

Cureus. 2025 Aug 8;17(8):e89616. doi: 10.7759/cureus.89616. eCollection 2025 Aug.

Abstract

INTRODUCTION

Venous thromboembolism (VTE), mainly deep vein thrombosis (DVT) and pulmonary embolism (PE), persists as a critical contributor to hospital-acquired mortality. Despite its largely preventable nature, early 2024 data from Bon Secours Hospital in Cork revealed alarmingly low compliance with VTE prophylaxis protocol.

AIM

This study evaluated the implementation efficacy of VTE risk assessment and prophylaxis in adult hospitalised patients at Bon Secours Hospital, Cork, according to National Institute for Health and Care Excellence (NICE) guidelines.

METHODOLOGY

Adult patients (127) at increased risk of VTE, specifically individuals aged ≥60 years, patients undergoing major surgical procedures, and/or patients with comorbidities including active cancer, hypertension, diabetes, immunological disorders, immobility or haematological disorders, across nine wards were included in this study. We also checked for any kind of bleeding risk, like active bleeding or low platelets. Each point was given 1 mark if present, which added to increase risk of VTE. We analysed the data to check the compliance with accurate prescription and completeness of the forms according to the NICE guideline. Exclusion criteria included paediatric, gynaecological, day-case admissions, and discharges within 24 hours of admission. The incomplete/inaccurate risk assessments were reported to improve timely and correct prophylaxis prescription.  Results: Compliance surged with assessment completion, reaching 111 out of 127 (87.39%) with prescription accuracy. Timely assessments within 24 hours accounted for 101 (79.52%), yet 16 (12.64%) remained unassessed. A substantial proportion (103, 80.23%) exhibited one or more VTE risk factors, predominantly advanced age and multiple comorbidities. Anticoagulants, particularly tinzaparin, constituted the principal prophylactic measure, with mechanical prophylaxis employed in only 15 (11.81%). Alarmingly, 22 (17.32%) of high-risk individuals were not prescribed any form of prophylaxis.

CONCLUSION

This study underscores the transformative impact of enforced protocol adherence and targeted multidisciplinary staff education on VTE prevention. The integration of an electronic health record system with real-time prompts could further ensure prophylaxis within the critical 24-hour window.

摘要

引言

静脉血栓栓塞症(VTE),主要包括深静脉血栓形成(DVT)和肺栓塞(PE),仍然是导致医院获得性死亡的一个关键因素。尽管其在很大程度上是可预防的,但2024年初科克博纳·塞库尔医院的数据显示,VTE预防方案的依从性低得惊人。

目的

本研究根据英国国家卫生与临床优化研究所(NICE)指南,评估了科克博纳·塞库尔医院成年住院患者VTE风险评估和预防的实施效果。

方法

本研究纳入了九个病房中VTE风险增加的成年患者(127例),特别是年龄≥60岁的个体、接受大手术的患者和/或患有包括活动性癌症、高血压、糖尿病、免疫紊乱、行动不便或血液系统疾病在内的合并症的患者。我们还检查了任何类型的出血风险,如活动性出血或血小板减少。如果存在,每个点给予1分,这会增加VTE风险。我们根据NICE指南分析数据,以检查准确处方的依从性和表格的完整性。排除标准包括儿科、妇科、日间手术入院以及入院后24小时内出院的患者。报告了不完整/不准确的风险评估,以促进及时和正确的预防处方。结果:随着评估的完成,依从性大幅提高,127例中有111例(87.39%)处方准确。24小时内及时评估的占101例(79.52%),但仍有16例(12.64%)未得到评估。很大一部分(103例,80.23%)表现出一种或多种VTE风险因素,主要是高龄和多种合并症。抗凝剂,尤其是替扎肝素,是主要的预防措施,仅15例(11.81%)采用了机械预防措施。令人担忧的是,22例(17.32%)高危个体未接受任何形式的预防治疗。

结论

本研究强调了严格遵守方案和有针对性的多学科工作人员教育对VTE预防的变革性影响。将电子健康记录系统与实时提示相结合可以进一步确保在关键的24小时窗口内进行预防。

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