Alkubaisi Mohammed A, Rajkanna Jeyanthy
Medicine, Peterborough City Hospital, Peterborough, GBR.
Diabetes and Endocrinology, Peterborough City Hospital, Peterborough, GBR.
Cureus. 2025 Aug 8;17(8):e89600. doi: 10.7759/cureus.89600. eCollection 2025 Aug.
Diabetic myonecrosis is an uncommon complication of poorly controlled diabetes mellitus. Usually, patients present with acute painful swelling of the affected muscles, mostly the quadriceps muscle of the thigh. We present the case of a 57-year-old male with type 2 diabetes mellitus who presented with progressive bilateral thigh pain and reduced movement. Blood results indicated slightly elevated creatine kinase, C-reactive protein, and erythrocyte sedimentation rate levels, and poor diabetes control. Magnetic resonance imaging showed features suggestive of myonecrosis. A muscle biopsy demonstrated active myofiber necrosis consistent with diabetic myonecrosis. The patient's symptoms improved after 11 days of treatment with intravenous fluids, painkillers, glycemic control, and physical therapy. This will highlight the importance of suspecting diabetic myonecrosis in patients presenting with bilateral acute swollen leg pain with a background of uncontrolled diabetes mellitus.
糖尿病性肌坏死是糖尿病控制不佳时一种罕见的并发症。通常，患者表现为受累肌肉急性疼痛性肿胀，主要是大腿的股四头肌。我们报告一例57岁2型糖尿病男性患者，其出现进行性双侧大腿疼痛及活动减少。血液检查结果显示肌酸激酶、C反应蛋白和红细胞沉降率水平略有升高，且糖尿病控制不佳。磁共振成像显示提示肌坏死的特征。肌肉活检显示与糖尿病性肌坏死一致的活动性肌纤维坏死。经静脉补液、止痛、血糖控制及物理治疗11天后，患者症状改善。这将凸显在有糖尿病控制不佳背景且出现双侧急性腿部肿胀疼痛的患者中怀疑糖尿病性肌坏死的重要性。
