Liang Shuyin, Luketich James D, Aranda-Michel Edgar, Baker Nicholas, Alicuben Evan, Levy Ryan M, Awais Omar, Gooding William E, Wang Hong, Sarkaria Inderpal, Christie Neil A, Schuchert Matthew J, Pennathur Arjun
Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Center, Pittsburgh, Pa.
UPMC Hillman Cancer Center Biostatistics Facility, Pittsburgh, Pa.
JTCVS Open. 2025 May 5;26:243-254. doi: 10.1016/j.xjon.2025.04.019. eCollection 2025 Aug.
Laparoscopic repair of giant paraesophageal hernia (LGPEHR) is a complex operation and typically includes an antireflux procedure (ARS); however, some patients without a history of reflux may be able to avoid an ARS. The objective of this study was to evaluate an alternative approach for giant paraesophageal hernia (GPEH) repair with restoration of the normal anatomy and an extended gastropexy in selected patients with minimal reflux symptoms.
Patients who underwent GPEH repair with an extended gastropexy were reviewed retrospectively. The procedure was not a "simple gastropexy." The LGPEHR included complete mediastinal dissection, hernia-sac reduction that restored anatomic intra-abdominal positioning of the stomach with careful preservation of the crura and vagal nerves, and tension-free crural repair. Then, an extended gastropexy was performed by placing a series of horizontal mattress sutures along the line of the short gastric vessels to the left crus and diaphragm. Perioperative outcomes, symptomatic improvement, recurrence, need for reoperation, and quality of life (Gastroesophageal Reflux Disease-Health-Related Quality of Life questionnaire) were evaluated.
A total of 114 patients (median age 77.4 years) underwent GPEH repair with gastropexy (elective n = 81; urgent/emergent n = 33). Perioperative complications occurred in 11 patients (9.6%). Dysphagia improved significantly ( < .01), and the median Gastroesophageal Reflux Disease-Health-Related Quality of Life score after GPEH repair was 2 (considered excellent). Imaging follow-up was performed at a median time of 14 months, with recurrence of hiatal hernia in 4 patients; 2 required reoperation.
LGPEHR with restoration of the normal anatomy and an extended gastropexy appears to be safe with good outcomes when key elements of repair are incorporated. If further validated, this option may be considered in selected high-risk patients who are not candidates for an ARS.
腹腔镜修复巨大食管旁疝(LGPEHR)是一项复杂手术,通常包括抗反流手术(ARS);然而,一些无反流病史的患者可能无需进行ARS。本研究的目的是评估一种用于巨大食管旁疝(GPEH)修复的替代方法,该方法能恢复正常解剖结构,并对反流症状轻微的特定患者进行扩大胃固定术。
回顾性分析接受扩大胃固定术修复GPEH的患者。该手术并非“简单的胃固定术”。LGPEHR包括完整的纵隔解剖、疝囊复位,使胃恢复至腹腔内正常解剖位置,同时小心保留膈脚和迷走神经,以及无张力膈脚修复。然后,通过沿着胃短血管至左膈脚和膈肌的连线放置一系列水平褥式缝线进行扩大胃固定术。评估围手术期结局、症状改善情况、复发情况、再次手术需求以及生活质量(胃食管反流病健康相关生活质量问卷)。
共有114例患者(中位年龄77.4岁)接受了胃固定术修复GPEH(择期手术n = 81;急诊/紧急手术n = 33)。11例患者(9.6%)发生围手术期并发症。吞咽困难显著改善(<0.01),GPEH修复术后胃食管反流病健康相关生活质量评分中位数为2(认为是优秀)。中位随访时间为14个月时进行影像学检查,4例患者出现食管裂孔疝复发;2例需要再次手术。
当纳入修复的关键要素时,恢复正常解剖结构并进行扩大胃固定术的LGPEHR似乎是安全的,且效果良好。如果进一步得到验证,对于不适合进行ARS的特定高危患者,可考虑采用此方法。