Wang Y, Shi X Q, Sun Y B
Contraception. 1985 Dec;32(6):651-60. doi: 10.1016/s0010-7824(85)80008-1.
Thirty-nine adult male Wistar rats were administered 20 mg/kg or 24.3 mg/kg polyvinylpyrrolidone-gossypol (PVP-G) and 20 mg/kg gossypol acetic acid (G-A) 6 times a week for 6 weeks. Mating test was taken to evaluate the antifertility effect. Caudal sperm count, body weight, sex and accessory sex organ weights were recorded. At the end of 6 weeks treatment, the recovery period of 6 weeks was investigated. The results showed that the onset of antifertility action and recovery with PVP-G are faster than with G-A.
