Alkan Selin, Erensoy Habib, Berkol Tonguc Demir
Department of Psychiatry, Ezine State Hospital, 17600 Canakkale, Turkey.
Department of Psychiatry, Uskudar University, Medical Faculty, 34768 Istanbul, Turkey.
Alpha Psychiatry. 2025 Aug 25;26(4):46029. doi: 10.31083/AP46029. eCollection 2025 Aug.
In bipolar disorder, residual mood symptoms often persist even during the euthymic period, impairing functionality in 30-60% of patients in clinical remission. Addressing residual symptoms is critical as they are linked to reduced functionality and subjective wellbeing. This cross-sectional study aimed to determine the relationship between mindful attention awareness (MASS) and residual symptom severity in bipolar I disorder.
This study included 100 patients with bipolar I disorder (BD-I) in remission, recruited consecutively from outpatient clinics between December, 2019 and March, 2020. The patients were evaluated using the sociodemographic data form, Hamilton Depression Rating Scale (HAM-D), Young Mania Rating Scale (YMRS), and Mindful Attention Awareness Scale (MAAS).
As the MAAS of the patients increases, their depressive symptoms decrease ( < 0.001). As the MAAS of the patients increases, their anxiety symptoms decrease ( < 0.001). No statistically significant relationship was found between the mindful attention awareness of the patients and their manic symptoms ( = 0.161). Two variables (HAM-D and Hamilton Anxiety Rating Scale Scores (HAM-A)) in the multiple linear regression model explain 21.8% of the change in MAAS score.
Residual depressive and anxiety symptoms are predictive of lower MAAS in bipolar I disorder. Incorporating strategies to manage residual mood symptoms and improve mindfulness may enhance functionality and facilitate complete remission. However, given the cross-sectional design and the lack of a control group, causal inferences cannot be made. Further longitudinal and interventional studies are needed to explore the efficacy of mindfulness-based approaches in BD-I and determine whether the observed associations are specific to this disorder.
在双相情感障碍中，即使在心境正常期，残留的情绪症状也常常持续存在，导致30%-60%临床缓解的患者功能受损。解决残留症状至关重要，因为它们与功能下降和主观幸福感降低有关。这项横断面研究旨在确定双相I型障碍中正念注意力觉知量表（MAAS）与残留症状严重程度之间的关系。
本研究纳入了100例处于缓解期的双相I型障碍（BD-I）患者，于2019年12月至2020年3月从门诊连续招募。使用社会人口统计学数据表、汉密尔顿抑郁量表（HAM-D）、杨氏躁狂量表（YMRS）和正念注意力觉知量表（MAAS）对患者进行评估。
随着患者MAAS得分增加，其抑郁症状减轻（<0.001）。随着患者MAAS得分增加，其焦虑症状减轻（<0.001）。未发现患者的正念注意力觉知与其躁狂症状之间存在统计学显著关系（=0.161）。多元线性回归模型中的两个变量（HAM-D和汉密尔顿焦虑量表评分（HAM-A））解释了MAAS得分变化的21.8%。
双相I型障碍中，残留的抑郁和焦虑症状预示着较低的MAAS得分。纳入管理残留情绪症状和提高正念的策略可能会增强功能并促进完全缓解。然而，鉴于横断面设计且缺乏对照组，无法进行因果推断。需要进一步的纵向和干预性研究来探索基于正念方法在双相I型障碍中的疗效，并确定观察到的关联是否特定于该障碍。
