Liu Jianjian, Shan Zhaozhao, Jian Xiangdong, Kan Baotian
Department of Poisoning and Occupational Diseases, Emergency Medicine, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Front Pharmacol. 2025 Aug 25;16:1567380. doi: 10.3389/fphar.2025.1567380. eCollection 2025.
Nicotine is a toxic alkaloid commonly found in tobacco products. This paper presents the clinical case of a patient who was exposed to a nicotine-laden waste liquid.
A 24-year-old male arrived at a local hospital in a state of coma and cardiac arrest. Following successful cardiopulmonary resuscitation, he was transferred to our facility for further treatment. Magnetic resonance imaging of the patient's head and neck revealed bilateral ischemic infarctions in the hippocampal region. After 24 days of treatment, the patient was discharged with significant improvement.
This case highlights the potential for severe clinical manifestations to arise shortly after a single exposure to a substantial amount of nicotine.
In clinical practice, it is crucial to promptly assess the patient's occupational history to identify the cause of the condition, closely monitor vital signs, and provide active supportive and symptomatic care. Additionally, this case underscores the importance of ensuring production safety and increasing awareness regarding occupational exposure risks.
尼古丁是一种常见于烟草制品中的有毒生物碱。本文介绍了一名接触含尼古丁废液患者的临床病例。
一名24岁男性昏迷并心脏骤停后被送至当地医院。心肺复苏成功后，他被转至我院进一步治疗。患者头颈部磁共振成像显示海马区双侧缺血性梗死。经过24天治疗，患者出院时病情明显改善。
该病例突出了单次接触大量尼古丁后不久出现严重临床表现的可能性。
在临床实践中，迅速评估患者职业史以确定病因、密切监测生命体征并提供积极的支持性和对症治疗至关重要。此外，该病例强调了确保生产安全和提高职业暴露风险意识的重要性。
