Gyan Kwadwo F, Opare-Addo Priscilla A, Siaw-Frimpong Moses, Ankomah Kwasi, Sarfo Fred S
Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Kwame Nkrumah University of Science & Technology, Kumasi, Ghana.
Ghana Med J. 2024 Jun;58(2):178-182. doi: 10.4314/gmj.v58i2.9.
Acute ischemic stroke management has evolved through several paradigms. Currently, thrombolysis is recommended for patients who present within 4.5 hours of acute ischemic stroke. Early neurological deterioration post-thrombolysis, however, may occur through several mechanisms. We report a case of a 66-year-old Ghanaian woman with multiple co-morbidities who presented with sudden onset right-sided weakness and aphasia of 2 hours duration. A diagnosis of acute ischemic stroke was made based on clinical examination and a computerised tomography scan of the brain. She underwent successful thrombolysis with recovery of full neurological function. She, however, developed a second ischemic stroke within 72 hours, with the likely aetiology being large vessel occlusion. This was subsequently managed conservatively. Extensive evaluation and control of specific stroke aetiologies is required for the prevention of stroke recurrence post thrombolysis. Also, the establishment of comprehensive stroke centres which provide neurovascular interventions in sub-Saharan Africa can help reduce stroke mortality and morbidity in eligible patients.
None declared.
急性缺血性卒中的治疗模式已经历了多次演变。目前,推荐对在急性缺血性卒中发病4.5小时内就诊的患者进行溶栓治疗。然而,溶栓后早期神经功能恶化可能通过多种机制发生。我们报告一例66岁患有多种合并症的加纳女性,她突发右侧肢体无力和失语2小时。根据临床检查和脑部计算机断层扫描诊断为急性缺血性卒中。她接受了成功的溶栓治疗,神经功能完全恢复。然而,她在72小时内发生了第二次缺血性卒中,可能的病因是大血管闭塞。随后对其进行了保守治疗。为预防溶栓后卒中复发,需要对特定的卒中病因进行广泛评估和控制。此外,在撒哈拉以南非洲建立提供神经血管介入治疗的综合卒中中心有助于降低符合条件患者的卒中死亡率和发病率。
未声明。