Schöpf J, Bryois C, Jonquiére M, Scharfetter C
Eur Arch Psychiatry Neurol Sci. 1985;235(3):164-70. doi: 10.1007/BF00380988.
A group of 80 women suffering from a severe psychiatric post-partum disorder and hospitalized for the first time in their lives was followed up between 4 and 35 years later. Besides the further evolution of psychic health of the patients, the occurrence of endogenous (i.e., functional) psychoses in first degree relatives was investigated. A global morbidity risk for endogenous psychoses of 10.9% was found, affective psychosis accounting for two-thirds of secondary cases. Subdivision of the sample according to the criterion of absence or presence of further psychotic episodes unrelated to childbirth revealed that first degree relatives of patients with exclusively puerperal decompensations had a low morbidity risk of 2.0%, but relatives of patients with later nonpuerperal episodes of illness one of 15.2%, the difference being statistically significant (P less than 0.002). This suggests that severe psychiatric disorders occurring exclusively in the post-partum period are nosologically distinct from those followed by nonpuerperal psychotic episodes of illness. Only the latter seem to be related to the traditionally recognized subgroups of endogenous psychoses.
一组80名患有严重产后精神障碍且首次住院治疗的女性在4至35年后接受了随访。除了患者心理健康的进一步发展情况外，还调查了一级亲属中内源性（即功能性）精神病的发病情况。发现内源性精神病的总体发病风险为10.9%，情感性精神病占继发性病例的三分之二。根据是否存在与分娩无关的进一步精神病发作这一标准对样本进行细分后发现，仅患有产褥期精神错乱的患者的一级亲属发病风险较低，为2.0%，但患有后期非产褥期疾病发作的患者的亲属发病风险为15.2%，差异具有统计学意义（P小于0.002）。这表明仅在产后期间发生的严重精神障碍在疾病分类学上与那些伴有非产褥期精神病发作的精神障碍不同。只有后者似乎与传统上公认的内源性精神病亚组有关。
