Brockington I F, Cernik K F, Schofield E M, Downing A R, Francis A F, Keelan C
Arch Gen Psychiatry. 1981 Jul;38(7):829-33. doi: 10.1001/archpsyc.1981.01780320109013.
Fifty-eight psychoses beginning within two weeks of childbirth are compared with 52 episodes of nonpuerperal psychotic illness occurring in young women. A clinical approach based on the use of multiple information sources and integrated assessment was used. Statistically significant differences between the two groups of patients were found in 52 of 214 psychopathological variables. Postpartum patients had more manic symptoms and "confusion," while nonpuerperal patients had more schizophrenic symptoms. The Research Diagnostic Criteria (RDC) showed an excess of schizoaffective (manic) puerperal patients and schizoaffective (depressed) or schizophrenic nonpuerperal patients. Only five of 58 puerperal episodes met RDC for schizophrenia. The relative lack of schizophrenic symptoms in the puerperal group was confirmed by self-ratings. The results are interpreted as supporting a link between puerperal psychosis and manic-depressive disease.
对58例产后两周内起病的精神病患者与52例年轻女性非产褥期精神病发作患者进行了比较。采用了基于多信息源使用和综合评估的临床方法。在214个精神病理变量中的52个变量上发现两组患者之间存在统计学上的显著差异。产后患者有更多的躁狂症状和“混乱”,而非产褥期患者有更多的精神分裂症症状。研究诊断标准(RDC)显示产褥期精神分裂情感性(躁狂)患者过多,而非产褥期精神分裂情感性(抑郁)或精神分裂症患者过多。58例产褥期发作中只有5例符合精神分裂症的RDC标准。产褥期组相对缺乏精神分裂症症状通过自评得到了证实。结果被解释为支持产褥期精神病与躁狂抑郁症之间的联系。