Broulik P D, Horký K, Pacovský V
Exp Clin Endocrinol. 1985 Dec;86(3):346-52. doi: 10.1055/s-0029-1210507.
Studies were performed in 86 patients with proven primary hyperparathyroidism pre-operatively and 6-7 months after parathyroidectomy. The 29% incidence of hypertension between patients with primary hyperparathyroidism is higher as compared with the incidence of hypertension in the general population. Systolic and diastolic blood pressures were significantly higher in patients with primary hyperparathyroidism before operation than after parathyroidectomy (p less than 0.001). In patients hypertensive before operation both the systolic and diastolic blood pressure significantly fell after parathyroidectomy (p less than 0.001). The blood pressure was found to have normalized in 13 of the 25 patients with hypertension. Renal damage and changes in renin levels are not the mechanisms in the production of hypertension in hyperparathyroid patients.
对86例经证实的原发性甲状旁腺功能亢进患者在术前及甲状旁腺切除术后6 - 7个月进行了研究。原发性甲状旁腺功能亢进患者中高血压的发生率为29%，高于普通人群中的高血压发生率。原发性甲状旁腺功能亢进患者术前的收缩压和舒张压显著高于甲状旁腺切除术后（p<0.001）。术前高血压患者在甲状旁腺切除术后收缩压和舒张压均显著下降（p<0.001）。25例高血压患者中有13例血压恢复正常。肾损害和肾素水平变化不是甲状旁腺功能亢进患者高血压产生的机制。
