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犬膀胱镜引导下男性犬壁内异位输尿管激光消融术:18例回顾性研究(2011 - 2023年)

Cystoscopic-Guided Laser Ablation of Intramural Ectopic Ureters in Male Dogs: A Retrospective Study of 18 Cases (2011-2023).

作者信息

Chang Josh S, Berent Allyson C, Weisse Chick W

机构信息

Schwarzman Animal Medical Center, New York, New York, USA.

出版信息

J Vet Intern Med. 2025 Sep-Oct;39(5):e70243. doi: 10.1111/jvim.70243.

DOI:10.1111/jvim.70243
PMID:40927962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12421311/
Abstract

BACKGROUND

There are limited studies on cystoscopic-guided laser ablation for treating ectopic ureters in male dogs. Further investigation is needed to assess its safety and efficacy.

HYPOTHESIS/OBJECTIVE: Retrospectively describe long-term outcomes in male dogs treated using cystoscopic-guided laser ablation of ectopic ureters (CLA-EU).

ANIMALS

Eighteen client-owned male dogs.

METHODS

Medical records of male dogs that had CLA-EU performed were retrospectively reviewed. Continence scores were assigned before and after the procedure. Data collected included signalment, neuter status, age of onset of urinary incontinence, pre- and post-operative continence scores, CBC, serum biochemistry, urinalysis, microbiological urine culture, pre- and post-operative abdominal imaging, EU laterality, concurrent anatomic anomalies, laser type and size used, procedure time, complications, and follow-up.

RESULTS

The procedure was performed successfully in all 28 ureters in the 18 dogs. Post-operative continence scores were significantly improved from pre-operative scores (p = 0.001). Four (22%) dogs were continent at the time of diagnosis. Of the 14 dogs initially incontinent, 11/14 (79%) became continent after CLA-EU without additional treatments, and an additional dog became continent with the addition of medications. Preoperatively, 14/28 kidneys and 17/28 ureters had evidence of hydronephrosis and hydroureter, respectively. Of the dogs, 10/14 with hydronephrosis and 12/17 with hydroureter showed improvement on post-operative ultrasonography. The median follow-up time was 1789 days (range, 98-3560).

CONCLUSION AND CLINICAL IMPORTANCE

In male dogs, CLA-EU was a safe, effective, and minimally invasive procedure with good to excellent short- and long-term outcomes, achieving continence in most dogs and improvement or stabilization of associated hydronephrosis and hydroureter.

摘要

背景

关于膀胱镜引导下激光消融治疗雄性犬异位输尿管的研究有限。需要进一步研究以评估其安全性和有效性。

假设/目的:回顾性描述采用膀胱镜引导下激光消融异位输尿管(CLA-EU)治疗的雄性犬的长期预后。

动物

18只客户拥有的雄性犬。

方法

对接受CLA-EU治疗的雄性犬的病历进行回顾性分析。在手术前后进行控尿评分。收集的数据包括特征、去势状态、尿失禁发病年龄、术前和术后控尿评分、血常规、血清生化、尿液分析、微生物尿培养、术前和术后腹部影像学检查、异位输尿管的侧别、并发解剖异常、使用的激光类型和尺寸、手术时间、并发症及随访情况。

结果

18只犬的28条输尿管均成功完成手术。术后控尿评分较术前显著改善(p = 0.001)。4只(22%)犬在诊断时即已控尿。在最初尿失禁的14只犬中,11/14(79%)在CLA-EU术后无需额外治疗即实现控尿,另有1只犬在添加药物后实现控尿。术前,28只肾脏中的14只和28条输尿管中的17条分别有肾积水和输尿管积水的证据。在这些犬中,10/14有肾积水和12/17有输尿管积水的犬在术后超声检查中显示病情改善。中位随访时间为1789天(范围98 - 3560天)。

结论及临床意义

在雄性犬中,CLA-EU是一种安全、有效且微创的手术,短期和长期预后良好至极佳,多数犬实现控尿,相关肾积水和输尿管积水得到改善或稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a69/12421311/4ccf846dfccd/JVIM-39-e70243-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a69/12421311/4ccf846dfccd/JVIM-39-e70243-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a69/12421311/4ccf846dfccd/JVIM-39-e70243-g001.jpg

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本文引用的文献

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Vet Surg. 2024 Apr;53(3):494-502. doi: 10.1111/vsu.14064. Epub 2024 Jan 29.
2
ACVIM consensus statement on diagnosis and management of urinary incontinence in dogs.ACVIM 共识声明:犬下泌尿道疾病的诊断与管理
J Vet Intern Med. 2024 Mar-Apr;38(2):878-903. doi: 10.1111/jvim.16975. Epub 2024 Jan 13.
3
Renal Agenesis, Extramural Ectopic Ureter, and Nonfunctioning Urinary Bladder: A Difficult Clinical Case with an Innovative Approach.
肾缺如、壁外异位输尿管和无功能膀胱:一例采用创新方法的疑难临床病例
Case Rep Vet Med. 2023 Jul 4;2023:3885397. doi: 10.1155/2023/3885397. eCollection 2023.
4
Prognostic factors for continence after surgical correction of ectopic ureters of 51 dogs with long-term follow-up.51 例具有长期随访的异位输尿管手术矫正后控尿的预后因素研究。
Acta Vet Scand. 2022 Nov 17;64(1):29. doi: 10.1186/s13028-022-00648-9.
5
Diagnostic yield of uroendoscopy compared to ultrasonography for evaluating lower urinary tract disorders in dogs.经尿道膀胱镜检查与超声检查诊断犬下尿路疾病的诊断率比较。
J Vet Intern Med. 2022 Sep;36(5):1700-1707. doi: 10.1111/jvim.16501. Epub 2022 Aug 19.
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