中国山西省农村成年人中多重疾病的患病率及模式：一项横断面研究的事后探索性亚组分析

Prevalence and patterns of multimorbidity among adults in rural Shanxi Province, China: A post-hoc exploratory subgroup analysis of a cross-sectional study.

作者信息

Tang Shuai, Li Yanxing, Li Runlan, Yang Hongmei, Hao Tianyou, Tian Maoyi, Zhang Xinyi, Feng Xiangxian, Li Zhifang

机构信息

School of Public Health, Shanxi Medical University, Taiyuan, China.

Academy of Medical Sciences, Shanxi Medical University, Taiyuan, China.

出版信息

PLoS One. 2025 Sep 10;20(9):e0330935. doi: 10.1371/journal.pone.0330935. eCollection 2025.

DOI:10.1371/journal.pone.0330935

PMID:40929110

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12422502/

Abstract

BACKGROUND

In China, the prevalence of chronic diseases is increasing, especially in rural areas, affecting younger populations and associating with multimorbidity. However, in resources-limited rural areas, there is a lack of primary data to the prevalence and patterns of multimorbidity in young populations. This study aims to analysis the differences in multimorbidity prevalence and patterns across different age groups and genders among adults in rural Shanxi Province.

METHODS

This study was a post-hoc analysis of a completed cross-sectional study. All the participants included in this post-hoc analysis were randomly selected from 80 villages from Shanxi Province. Multimorbidity, defined as the coexistence of two or more diseases in same individual, was assessed by collecting primary data (questionnaires and physical examinations) and routine data (health insurance claims and hospital electronic records).

RESULTS

A total of 2,208 participants were included, with a mean age of 57.7 ± 10.5 years. 1283 (58.1%) were aged 30-59 years and 1152 (52.2%) were females. There were 1524 cases (69.0%) with disease and 818 cases (37.5%) with multimorbidity. Hypertension had the highest prevalence (43.5%) as well as multimorbidity pattern was often associated with it (75.3%). The three most common dyad multimorbidity patterns were hypertension and stroke, heart disease, and chronic digestive diseases, respectively. Among 30-59 years, it was hypertension respectively and stroke, chronic digestive diseases, and arthritis, while among ≥60 years, it was hypertension respectively and stroke, heart disease, and diabetes. In males, it was hypertension respectively and stroke, heart disease, and chronic digestive diseases, while in females it was hypertension respectively and arthritis, chronic digestive diseases, and diabetes.

CONCLUSION

The multimorbidity prevalence among adults in rural Shanxi Province is notably high. The pattern of multimorbidity is distinct differences between age groups and genders, suggesting that prevention and management of priority diseases in specific populations should be targeted.

摘要

背景

在中国，慢性病的患病率正在上升，特别是在农村地区，影响着较年轻的人群，且与多种疾病并存相关。然而，在资源有限的农村地区，缺乏关于年轻人群中多种疾病并存的患病率和模式的原始数据。本研究旨在分析山西省农村成年人中不同年龄组和性别在多种疾病并存的患病率和模式上的差异。

方法

本研究是对一项已完成的横断面研究的事后分析。本次事后分析纳入的所有参与者均从山西省的80个村庄中随机选取。通过收集原始数据（问卷和体格检查）以及常规数据（医疗保险理赔和医院电子记录）来评估多种疾病并存情况，即同一人同时存在两种或更多种疾病。

结果

共纳入2208名参与者，平均年龄为57.7±10.5岁。1283人（58.1%）年龄在30至59岁之间，1152人（52.2%）为女性。有1524例（69.0%）患有疾病，818例（37.5%）患有多种疾病。高血压患病率最高（43.5%），且多种疾病并存模式常与之相关（75.3%）。三种最常见的二元多种疾病并存模式分别是高血压与中风、心脏病以及慢性消化系统疾病。在30至59岁人群中，分别是高血压与中风、慢性消化系统疾病以及关节炎，而在60岁及以上人群中，分别是高血压与中风、心脏病以及糖尿病。在男性中，分别是高血压与中风、心脏病以及慢性消化系统疾病，而在女性中，分别是高血压与关节炎、慢性消化系统疾病以及糖尿病。