Coelho Luiz Gonzaga Vaz, Chinzon Décio, Ribeiro Laércio Tenório, Sanches Bruno Squárcio Fernandes, Delgado Áureo de Almeida, Vilela Eduardo Garcia
Hospital das Clínicas da Universidade Federal de Minas Gerais/Ebserh, Instituto Alfa de Gastroenterologia; Belo Horizonte, MG, Brasil.
Hospital das Clínicas da Universidade de São Paulo, Departamento de Gastroenterologia, São Paulo, SP, Brasil.
Arq Gastroenterol. 2025 Sep 5;62:e25019. doi: 10.1590/S0004-2803.24612025-019. eCollection 2025.
Most Helicobacter pylori (H. pylori) infections are acquired in childhood. It remains uncertain whether gastroenterologists involved in endoscopic procedures face an increased occupational risk of H. pylori.
To determine H. pylori prevalence among gastroenterologists and gastroendoscopists in Brazil.
A prospective, observational, non-interventional study was conducted during the 2022 Brazilian Digestive Disease Week meeting. Attendees were invited to undergo a 13C-urea breath test (UBT) to investigate their H. pylori status. The attendees completed a questionnaire regarding their demographic data and information about medical specialties and activities (gastroenterology or gastroendoscopy). This study included 286 participants (160 women, 126 men; mean age, 42 years; SD, 13, range 25-83 years) agreed to participate. 13C-urea breath test: Before the study, all participants abstained from proton pump inhibitors (PPIs) and H2 blockers for 1 week, and antibiotics for four weeks. The test was performed after at least one-hour of fasting using the BreathID HP Lab System® (Exalenz Bioscience, Israel, now Meridian Bioscience, USA), with a delta over baseline (DOB) ≥5‰ indicated H. pylori infection.
Among the 286 study participants, 218 tested negative and 68 tested positive with an overall prevalence of 23.8%. If we excluded all 67 participants who reported prior treatment for HP infection (54 HP-ve and 13 HP+ve) from the analysis of our sample, our sample of 219 participants presented a current prevalence of 25.1% (55 HP+ve and 164 HP-ve). The HP prevalence among participants who did or did not perform endoscopic procedures in their daily activities was 28.4% and 23.2%, respectively, with no statistically significant difference (P=0.39).
The prevalence of H. pylori infection among Brazilian gastroenterologists is moderate, with one in four professionals still infected. H. pylori infection prevalence increases with age and is higher among overweight and obese individuals. Performing endoscopic procedures does not appear to increase the risk of infections among gastroenterologists in Brazil.
大多数幽门螺杆菌（H. pylori）感染是在儿童时期获得的。参与内镜检查的胃肠病学家是否面临更高的幽门螺杆菌职业感染风险仍不确定。
确定巴西胃肠病学家和胃肠内镜医师中幽门螺杆菌的感染率。
在2022年巴西消化疾病周会议期间进行了一项前瞻性、观察性、非干预性研究。邀请与会者接受13C尿素呼气试验（UBT）以调查其幽门螺杆菌感染状况。与会者完成了一份关于其人口统计学数据以及医学专业和活动（胃肠病学或胃肠内镜检查）的问卷。本研究纳入了286名同意参与的参与者（160名女性，126名男性；平均年龄42岁；标准差13，年龄范围25 - 83岁）。13C尿素呼气试验：在研究前，所有参与者停用质子泵抑制剂（PPI）和H2受体阻滞剂1周，停用抗生素4周。使用BreathID HP Lab System®（以色列Exalenz Bioscience公司，现美国Meridian Bioscience公司）在至少禁食1小时后进行测试，基线以上差值（DOB）≥5‰表明幽门螺杆菌感染。
在286名研究参与者中，218人检测为阴性，68人检测为阳性，总体感染率为23.8%。如果在样本分析中排除所有67名报告曾接受过幽门螺杆菌感染治疗的参与者（54名幽门螺杆菌阴性和13名幽门螺杆菌阳性），我们的219名参与者样本的当前感染率为25.1%（55名幽门螺杆菌阳性和164名幽门螺杆菌阴性）。日常活动中进行或未进行内镜检查的参与者中幽门螺杆菌感染率分别为28.4%和23.2%，差异无统计学意义（P = 0.39）。
巴西胃肠病学家中幽门螺杆菌感染率中等，每四名专业人员中仍有一人感染。幽门螺杆菌感染率随年龄增长而增加，超重和肥胖个体中的感染率更高。在巴西，进行内镜检查似乎不会增加胃肠病学家的感染风险。
