Hanya S, Sugawara M, Inage H, Ishihara A
Heart Vessels. 1985 Feb;1(1):36-42. doi: 10.1007/BF02066485.
A new method of evaluating the degree of stenosis using the pressure loss coefficient is presented here. The pressure loss coefficient was obtained in patients with pulmonary or aortic stenosis by measuring the pressure and velocity of the blood simultaneously with a multisensor catheter. Although the pressure gradient across the stenosis was augmented by increasing the blood velocity with pharmacological loading, the pressure loss coefficient remained nearly constant. This confirmed that the pressure loss coefficient is more appropriate for evaluating the degree of stenosis than the pressure gradient, which depends on the blood velocity. The pressure loss coefficients obtained from the preoperative and postoperative catheterization data were compared to evaluate the effects of the surgical operation. A pressure loss coefficient of 15 was proposed as the critical value for the indication of operation.
本文提出了一种使用压力损失系数评估狭窄程度的新方法。通过使用多传感器导管同时测量血液的压力和流速,获得了患有肺动脉或主动脉狭窄患者的压力损失系数。尽管通过药物负荷增加血流速度会使狭窄两端的压力梯度增大,但压力损失系数几乎保持不变。这证实了与依赖于血流速度的压力梯度相比,压力损失系数更适合评估狭窄程度。比较术前和术后导管插入数据获得的压力损失系数,以评估手术效果。提出压力损失系数15作为手术指征的临界值。