Minerva M, Perilli L, Francioni A, Lotti F, Curcio M R, Grosso S
Clinical Pediatrics, Department of Molecular Medicine and Development, Azienda Ospedaliero-Universitaria Senese, University of Siena, Siena, Italy.
Front Pediatr. 2025 Aug 26;13:1653744. doi: 10.3389/fped.2025.1653744. eCollection 2025.
Febrile myoclonus (FM) is a benign condition characterized by the sudden onset of generalized, multifocal, or segmental jerks during fever, without signs of central nervous system infections, resolving as the temperature elevation subsides. This condition is poorly described in literature, and its incidence is not well identified. We present the case of a 1-year-old child who developed myoclonic jerks during a febrile episode, diagnosed with FM. The child exhibited a normal neurological examination and neuromotor development appropriate for age. The electroencephalogram (EEG) showed no epileptiform discharges during the events, and past medical or familiar history was negative for epilepsy or any other neurological condition. We conducted a narrative review of the current literature to improve understanding of this benign clinical manifestation. Additionally, we included audio and video material to aid physicians in recognizing the condition, avoiding unnecessary diagnostic procedures and overtreatment with antiseizure medications. Our goal is to increase awareness of this rare phenomenon and expand its phenotypical spectrum.
发热性肌阵挛（FM）是一种良性病症，其特征为发热期间突然出现全身性、多灶性或节段性抽搐，无中枢神经系统感染迹象，随着体温升高消退而缓解。这种病症在文献中描述较少，其发病率也未明确确定。我们报告一例1岁儿童，在发热发作期间出现肌阵挛性抽搐，诊断为FM。该儿童神经系统检查正常，神经运动发育与年龄相符。事件发生期间脑电图（EEG）未显示癫痫样放电，既往病史或家族史无癫痫或任何其他神经系统疾病。我们对当前文献进行了叙述性综述，以增进对这种良性临床表现的理解。此外，我们纳入了音频和视频资料，以帮助医生识别这种病症，避免不必要的诊断程序和抗癫痫药物的过度治疗。我们的目标是提高对这种罕见现象的认识，并扩大其表型谱。
