Set Htet Htet Myo, Sann Khin Ni, Shanmugasundaram Ramkumar
Cancer Center, University Hospital Southampton NHS Foundation Trust, Southampton, GBR.
Cureus. 2025 Sep 9;17(9):e91903. doi: 10.7759/cureus.91903. eCollection 2025 Sep.
Hydrocephalus is a known tumour complication associated with vestibular schwannomas, which can be either the obstructive or communicating (non-obstructive) type. The latter represents a rare and controversial complication following radiotherapy, typically resulting from tumour necrosis. Management generally involves cerebrospinal fluid diversion. Here, we present a case of normal-pressure and communicating hydrocephalus that developed after radiotherapy for a vestibular schwannoma. The patient was a 72-year-old woman who initially presented with imbalance and right sensorineural hearing loss. An MRI scan identified an enhancing mass in the right cerebellopontine angle and the right internal auditory meatus, consistent with a diagnosis of a right vestibular schwannoma. Following evidence of increased tumour growth on subsequent MRI scans, the patient underwent radiotherapy with a total dose of 50 Gy delivered in 30 fractions, utilising the volumetric modulated arc therapy technique. Sixteen months after radiotherapy, the patient experienced new neurological symptoms, including intermittent slurred speech, loss of concentration, slow cognition, right facial asymmetry, numbness, and recurrent falls. CT of the head showed communicating hydrocephalus. Therefore, a left ventriculoperitoneal shunt was subsequently inserted for the management of hydrocephalus. However, due to shunt blockage, the patient underwent near-total resection of the enlarging vestibular schwannoma and has since been followed by the neurosurgical team.
脑积水是一种已知的与前庭神经鞘瘤相关的肿瘤并发症,可为梗阻性或交通性(非梗阻性)类型。后者是放疗后一种罕见且存在争议的并发症,通常由肿瘤坏死引起。治疗一般包括脑脊液分流。在此,我们报告一例前庭神经鞘瘤放疗后发生的常压性交通性脑积水病例。患者为一名72岁女性,最初表现为平衡失调和右侧感音神经性听力丧失。磁共振成像(MRI)扫描显示右侧桥小脑角和右侧内耳道有一强化肿块,符合右侧前庭神经鞘瘤的诊断。在后续MRI扫描显示肿瘤生长加快后,患者接受了放疗,采用容积调强弧形放疗技术,分30次给予总剂量50 Gy。放疗16个月后,患者出现新的神经症状,包括间歇性言语不清、注意力不集中、认知迟缓、右侧面部不对称、麻木和反复跌倒。头部CT显示交通性脑积水。因此,随后为患者置入了左心室-腹腔分流管以治疗脑积水。然而,由于分流管堵塞,患者接受了扩大的前庭神经鞘瘤近全切除术,此后一直由神经外科团队随访。