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社区药剂师在为居家患者优化药物治疗中的作用:一项范围综述

The role of community pharmacists in medicines optimisation for housebound people: A scoping review.

作者信息

Blease Jennifer, Bhonsle Yahvi, Ireson Rose, Farroha Albert, Westley Greg, Cooper Richard, Hind Daniel

机构信息

The Medical School, University of Sheffield, Sheffield, United Kingdom.

NHS South Yorkshire ICB, South Yorkshire, United Kingdom.

出版信息

PLoS One. 2025 Sep 11;20(9):e0331294. doi: 10.1371/journal.pone.0331294. eCollection 2025.

Abstract

BACKGROUND

An increasingly ageing population presents many challenges for healthcare systems, including how to support older adults who are more likely to be both housebound and have complex medication needs. Community pharmacists may play a key role in medicines optimisation for this vulnerable population, however, the extent of literature exploring this topic is unclear.

OBJECTIVE

To map existing literature on the role of community pharmacists in medicines optimisation for housebound older adults in the United Kingdom (UK).

METHODS

A scoping review was conducted following PRISMA-ScR guidelines. Peer-reviewed primary research and grey literature published since 2000 were searched using relevant databases and websites. Data was charted using a standardised form based on TIDieR guidelines and EPOC taxonomies. A narrative synthesis was conducted to summarise and interpret the findings from included studies.

RESULTS

Seven sources were included in the review - five peer-reviewed articles and two grey literature reports. Interventions consisted of domiciliary medication reviews conducted by pharmacists. Key medicines optimisation strategies addressed were medication review, deprescribing, addressing polypharmacy and facilitating communication between providers. Reported outcomes included identification of widespread issues with polypharmacy and medication-related problems, reduced hospital admissions, cost savings and improved patient care. Gaps identified were limited generalisability, lack of comparisons to standard care, and under-representation of minority groups.

CONCLUSIONS

The literature indicates promise for the role of community pharmacists in medicines optimisation for housebound older adults through domiciliary services. However, more research is needed to evaluate the effectiveness and feasibility of pharmacist-led interventions in this setting. Addressing identified gaps will help inform pharmacists' roles in supporting medication needs of housebound patients.

摘要

背景

人口老龄化加剧给医疗保健系统带来了诸多挑战,包括如何为那些更有可能居家且有复杂用药需求的老年人提供支持。社区药剂师可能在优化这一弱势群体的用药方面发挥关键作用,然而,探讨该主题的文献数量尚不清楚。

目的

梳理关于英国社区药剂师在为居家老年人优化用药方面作用的现有文献。

方法

按照PRISMA-ScR指南进行了一项范围综述。使用相关数据库和网站检索了自2000年以来发表的同行评审的原始研究和灰色文献。基于TIDieR指南和EPOC分类法,使用标准化表格对数据进行了图表绘制。进行了叙述性综合分析,以总结和解释纳入研究的结果。

结果

该综述纳入了七个来源——五篇同行评审文章和两份灰色文献报告。干预措施包括药剂师进行的居家用药审查。所涉及的关键用药优化策略包括用药审查、减少用药、解决多重用药问题以及促进提供者之间的沟通。报告的结果包括识别出多重用药和与用药相关问题的普遍存在、减少住院次数、节省成本以及改善患者护理。发现的差距包括普遍适用性有限、缺乏与标准护理的比较以及少数群体代表性不足。

结论

文献表明社区药剂师通过居家服务在为居家老年人优化用药方面的作用具有前景。然而,需要更多研究来评估药剂师主导的干预措施在这种情况下的有效性和可行性。解决已发现的差距将有助于明确药剂师在支持居家患者用药需求方面的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14f8/12425228/cefbbeeea7d8/pone.0331294.g001.jpg

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