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特发性牵引性瞳孔异位合并永存瞳孔膜的成功手术治疗。病例报告。

Successful surgical treatment of idiopathic tractional corectopia complicated by persistent pupillae membrane. Case report.

作者信息

Bobrova N, Dovhan O, Romanova T

机构信息

Pediatric Ophthalmic Pathology Department, SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine", 49/51 Frantsuzkyi Bulvar, Odesa, 65015, Ukraine.

出版信息

Int J Surg Case Rep. 2025 Oct;135:111908. doi: 10.1016/j.ijscr.2025.111908. Epub 2025 Sep 3.

DOI:10.1016/j.ijscr.2025.111908
PMID:40934679
Abstract

INTRODUCTION

Idiopathic tractional corectopia (ITC) is a rare congenital anomaly affecting the pupil's position and shape. In the literature, there are isolated cases of surgical treatment for ITC, which caused visual axis obstruction.

CASE PRESENTATION

А 1-year-old child complained of low vision in the left eye and was diagnosed with ITC, microcoria, discoria, persistent pupillary membrane (PPM), anterior embryotoxon, and microphthalmos. Surgical removal of PPM with anterior embryotoxin was performed, restoring the pupil's size, position, and shape. Lens transparency was preserved. The anatomical structure of the anterior eye was restored. Postoperatively, the child received local/generalanti-inflammatory therapy and pupil massage. IOP remained normal, and VA improved to 0.13 Teller's cards (0.9 logMAR). At 12 months after surgery, stable optical and cosmetic results were observed with VA increased to 0.2 Teller's cards (0.7 logMAR).

CLINICAL DISCUSSION

ITC is combined with PPM, usually unilateral, and can progress, leading to visual axis obstruction and amblyopia development. Various treatments have been proposed, involving PPM strand dissection and pupil sphincterotomy, which can cause complications such as loss of pupil shape and ability to dilate evenly, resulting in a cosmetic defect. The newly developed surgical technique helps prevent these complications.

CONCLUSION

The case demonstrates the restoration of pupil position, size, shape, and function in ITC, achieved by atraumatic PPM removal as opposed to sphincterotomy. Preservation of lens transparency and accommodative ability improved VA and prevented amblyopia development. For the first time, surgical anterior embryotoxon removal without complications for the cornea, iris, and anterior chamber angle was described.

摘要

引言

特发性牵引性瞳孔异位(ITC)是一种罕见的先天性异常,会影响瞳孔的位置和形状。文献中有ITC的孤立手术治疗病例,这些病例导致了视轴阻塞。

病例报告

一名1岁儿童因左眼视力低下就诊,被诊断为ITC、小瞳孔、瞳孔不等大、永存瞳孔膜(PPM)、前胚胎毒素和小眼球。进行了PPM与前胚胎毒素的手术切除,恢复了瞳孔的大小、位置和形状。晶状体透明度得以保留。眼前部的解剖结构得以恢复。术后,患儿接受了局部/全身抗炎治疗和瞳孔按摩。眼压保持正常,视力提高到0.13泰勒卡片(0.9 logMAR)。术后12个月,观察到稳定的光学和美容效果,视力提高到0.2泰勒卡片(0.7 logMAR)。

临床讨论

ITC常合并PPM,通常为单侧,且可进展,导致视轴阻塞和弱视发展。已提出了各种治疗方法,包括PPM条索分离和瞳孔括约肌切开术,但这些方法可能会导致诸如瞳孔形状丧失和均匀扩张能力丧失等并发症,从而造成美容缺陷。新开发的手术技术有助于预防这些并发症。

结论

该病例展示了通过无创伤性切除PPM而非括约肌切开术,恢复了ITC患者瞳孔的位置、大小、形状和功能。晶状体透明度和调节能力的保留改善了视力并预防了弱视发展。首次描述了无角膜、虹膜和前房角并发症的手术切除前胚胎毒素的方法。

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