Hildebrandt Anke, Bornemann Reinhard
Medizinische Klinik I, St. Vincenz-Krankenhaus, Datteln, Germany.
Institut für Medizinische Mikrobiologie, Universität Münster, Münster, Germany.
Z Gastroenterol. 2025 Sep;63(9):922-929. doi: 10.1055/a-2645-6481. Epub 2025 Sep 11.
The treatment of infection, so far, focussed on empirical antibiotic regimens. Facing increasing resistance dynamics and regionally different resistance patterns, however, resistance testing respectively resistance-guided therapy appears to be more appropriate. This helds not only in order to increase the effectiveness of individual therapy, but also in the sense of antibiotic stewardship. In particular, in the context of predominantly gastroscopic diagnostics, various options for resistance testing using culture and PCR are available. Thus, the optimal resistance-oriented therapy regimens can be derived on an individual basis.
到目前为止，感染的治疗主要集中在经验性抗生素治疗方案上。然而，面对日益增加的耐药动态和地区性不同的耐药模式，耐药性检测以及耐药性引导的治疗似乎更为合适。这不仅是为了提高个体治疗的有效性，也是从抗生素管理的角度而言。特别是在主要进行胃镜诊断的情况下，可以采用多种利用培养和PCR进行耐药性检测的方法。因此，可以根据个体情况制定最佳的以耐药性为导向的治疗方案。
