[双剂量T1-201心肌显像评估右心室冠状动脉储备]

[Coronary reserve of the right ventricle evaluated by double dose T1-201 scintigraphy].

作者信息

Sugihara H, Adachi H, Nakagawa H, Nishida K, Kitamura H, Koda M, Higami M, Furukawa K, Katsume H, Ijichi H

出版信息

J Cardiogr. 1985 Jun;15(2):297-305.

Abstract

Thallium-201 double dose scintigraphy was applied to exercise to estimate the coronary blood flow reserve of the left and right ventricles and this was compared with the degree of coronary artery stenosis. As an index of coronary reserve we measured the rate of change of blood flow distribution (delta F) calculated from the change in myocardial radioactivity following thallium-201 injections, once at rest and once during exercise. With submaximal exercise the increases in delta F of the left ventricle were less in patients with ischemic heart disease than in the control subjects, and were less as the number of diseased coronary vessels increased. The increases of delta F of the right ventricle were less in patients with stenosis of the proximal portion of the right coronary artery than in patients without stenosis and in the control subjects. The more severe the stenosis of the proximal portion of the right coronary artery, the smaller the delta F of the right ventricle. These results indicate that evaluation of the delta F in the left and right ventricles is useful in estimating coronary artery stenosis.

摘要

应用铊-201双剂量闪烁扫描术进行运动试验，以评估左、右心室的冠状动脉血流储备，并将其与冠状动脉狭窄程度进行比较。作为冠状动脉储备的指标，我们测量了血流分布变化率（δF），该指标通过静息和运动时注射铊-201后心肌放射性的变化计算得出。在次极量运动时，缺血性心脏病患者左心室δF的增加幅度小于对照组，且随着病变冠状动脉数量的增加而减小。右冠状动脉近端狭窄患者右心室δF的增加幅度小于无狭窄患者及对照组。右冠状动脉近端狭窄越严重，右心室的δF越小。这些结果表明，评估左、右心室的δF有助于估计冠状动脉狭窄。