Takahashi M, Shimada H, Yanagisawa H, Katagiri S, Kobayashi H
J Cardiogr. 1985 Jun;15(2):535-42.
The hemodynamics of fetal hearts, possibly having right ventricular overload were investigated using pulsed Doppler and cross-sectional echocardiography. The subjects consisted of 250 normal fetuses at 30 to 38 weeks gestation, 23 of which were studied by Doppler method. The ultrasonic beam was directed toward the centers of the tricuspid and mitral orifices imaged in the apical four-chamber view to record right ventricular and left ventricular inflow velocities. The flow velocity patterns of right and left ventricular inflow tracts were similar and consisted of two peaks; the rapid filling phase and the atrial contraction phase. The peak velocity of the atrial contraction phase was slightly greater than that of the rapid filling phase. Mitral peak flow velocity was 52.1 +/- 9.9 cm/sec (mean +/- SD), while tricuspid peak flow velocity was 56.1 +/- 8.7 cm/sec, and the ratio of the latter to the former was 1.09 +/- 0.09. We calculated the excursions and diastolic descent rate (DDR) of the mitral and tricuspid valves using M-mode echocardiography, which were also strongly affected by stroke volume. TV DDR/MV DDR = 1.06 +/- 0.10, and TV excursion/MV excursion = 1.09 +/- 0.09. Reportedly, 2/3 of the total cardiac volume entered the right ventricle, based on the experimental study of fetal lambs. However, the results obtained in the present study suggest that the right ventricular flow volume may be only slightly greater than that of the left ventricle.
采用脉冲多普勒和横截面超声心动图对可能存在右心室负荷过重的胎儿心脏血流动力学进行了研究。研究对象包括250例妊娠30至38周的正常胎儿,其中23例采用多普勒方法进行研究。超声束指向心尖四腔心切面中成像的三尖瓣和二尖瓣口中心,以记录右心室和左心室的流入速度。右心室和左心室流入道的流速模式相似,均由两个峰值组成;快速充盈期和心房收缩期。心房收缩期的峰值速度略大于快速充盈期。二尖瓣峰值流速为52.1±9.9厘米/秒(平均值±标准差),而三尖瓣峰值流速为56.1±8.7厘米/秒,后者与前者的比值为1.09±0.09。我们使用M型超声心动图计算了二尖瓣和三尖瓣的活动幅度和舒张期下降速率(DDR),它们也受到每搏量的强烈影响。三尖瓣DDR/二尖瓣DDR = 1.06±0.10,三尖瓣活动幅度/二尖瓣活动幅度 = 1.09±0.09。据报道,基于对胎羊的实验研究,心脏总体积的2/3进入右心室。然而,本研究获得的结果表明,右心室的血流量可能仅略大于左心室。