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Transient Formation of Stress Granules Disturbs Neural Stem Cell Differentiation.

作者信息

Wang Mengmeng, Wang Yarong, Ma Hongyu, Liu Hanze, Lu Yating, Zhang Yaozhong, Huang Zhihui, Dong Songqi, Zhang Kun, Wu Shengxi, Wang Yazhou

机构信息

Department of Neurobiology and Institute of Neurosciences, School of Basic Medicine, Fourth Military Medical University, Xi'an, 710032, China.

Department of Neurobiology, Hebei Medical University, Shijiazhuang, 050017, China.

出版信息

Neurosci Bull. 2025 Sep 12. doi: 10.1007/s12264-025-01503-3.

DOI:10.1007/s12264-025-01503-3
PMID:40938536
Abstract
摘要

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本文引用的文献

1
Stress granule formation helps to mitigate neurodegeneration.应激颗粒的形成有助于减轻神经退行性病变。
Nucleic Acids Res. 2024 Sep 9;52(16):9745-9759. doi: 10.1093/nar/gkae655.
2
QKI shuttles internal mG-modified transcripts into stress granules and modulates mRNA metabolism.QKI 将内源性 mG 修饰的转录本穿梭到应激颗粒中,并调节 mRNA 代谢。
Cell. 2023 Jul 20;186(15):3208-3226.e27. doi: 10.1016/j.cell.2023.05.047. Epub 2023 Jun 27.
3
Axin2 coupled excessive Wnt-glycolysis signaling mediates social defect in autism spectrum disorders.
Axin2 介导的 Wnt-糖酵解信号通路过度激活导致自闭症谱系障碍的社交缺陷。
EMBO Mol Med. 2023 Jun 7;15(6):e17101. doi: 10.15252/emmm.202217101. Epub 2023 Apr 20.
4
Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.多种遗传性运动感觉神经病2型(CMT2)与应激颗粒中异常的G3BP相互作用有关。
Cell. 2023 Feb 16;186(4):803-820.e25. doi: 10.1016/j.cell.2022.12.046. Epub 2023 Feb 3.
5
The impact of (ab)normal maternal environment on cortical development.异常母体环境对皮质发育的影响。
Prog Neurobiol. 2021 Jul;202:102054. doi: 10.1016/j.pneurobio.2021.102054. Epub 2021 Apr 24.
6
TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau.TIA1 增强 tau 相分离并促进毒性寡聚 tau 的产生。
Proc Natl Acad Sci U S A. 2021 Mar 2;118(9). doi: 10.1073/pnas.2014188118.
7
Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules.单分子成像揭示定位于应激颗粒的 mRNAs 的翻译。
Cell. 2020 Dec 23;183(7):1801-1812.e13. doi: 10.1016/j.cell.2020.11.010. Epub 2020 Dec 11.
8
Chronic stress induces formation of stress granules and pathological TDP-43 aggregates in human ALS fibroblasts and iPSC-motoneurons.慢性应激诱导人肌萎缩侧索硬化症成纤维细胞和 iPSC 运动神经元中应激颗粒和病理性 TDP-43 聚集体的形成。
Neurobiol Dis. 2020 Nov;145:105051. doi: 10.1016/j.nbd.2020.105051. Epub 2020 Aug 20.
9
Changing faces of stress: Impact of heat and arsenite treatment on the composition of stress granules.应激的变化面貌:热和亚砷酸盐处理对应激颗粒组成的影响
Wiley Interdiscip Rev RNA. 2020 Nov;11(6):e1596. doi: 10.1002/wrna.1596. Epub 2020 May 3.
10
Stress granules and neurodegeneration.应激颗粒与神经退行性变。
Nat Rev Neurosci. 2019 Nov;20(11):649-666. doi: 10.1038/s41583-019-0222-5. Epub 2019 Oct 3.